AI Article Synopsis
- Fever of unknown origin can be challenging to diagnose, particularly due to the potential for serious conditions like endocarditis, especially in patients with existing heart issues.
- The differential diagnosis is complicated by overlapping symptoms from various conditions, including infections, autoimmune diseases, and cancers.
- The case study highlights a patient with fever and skin nodules who was ultimately diagnosed with Wegener's granulomatosis, despite a history of mitral valve prolapse.
Article Abstract
Fever of unknown origin is one of the most intriguing issues in clinical practice. One of the most feared diagnoses, especially in patients with known valvular disease, is endocarditis. The differential diagnosis of fever is often complicated by the clinical-pathological overlap between the systemic inflammatory response in different types of pathologies such as infectious, autoimmune or neoplastic disorders. We report a case of a patient presenting with fever, cutaneous nodules and malaise, with a known mitral valve prolapse and moderate regurgitation, in which the diagnosis of Wegener's granulomatosis was finally made.
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