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Hemolysis due to anti-IH in a patient with beta-thalassemia and infection.
Immunohematology
December 2024
Department of Pathology, University of California San Diego, La Jolla, CA.
Anti-IH is a common cold agglutinin that is typically clinically insignificant. We present a case that resulted in hemolysis. A 32-year-old male patient with transfusion-independent beta-thalassemia intermedia presented with symptomatic anemia.
View Article and Find Full Text PDFTransient suppression of high-prevalence Kell blood group antigens and concomitant development of a Kell-related antibody that appears to recognize a high-prevalence Kell antigen not previously defined.
Immunohematology
December 2024
International Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, UK.
A previously healthy 32-year-old male patient was admitted to hospital with malaise, dyspnea, anemia, thrombocytopenia, and leukopenia. Anemia and thrombocytopenia worsened during the third week. Considering the possible need for transfusion, routine ABO and D typing and an antibody detection test were performed.
View Article and Find Full Text PDFHeavy menstrual bleeding in adolescents: Evaluation of diagnostic indicators and treatment preferences.
Int J Gynaecol Obstet
December 2024
Department of Pediatrics, Division of Pediatric Emergency Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Objective: Heavy menstrual bleeding (HMB) is a significant health concern that may lead to critical medical care and impaired quality of life. The aim of the present study was to identify the clinical indicators of common causes of HMB in adolescents and evaluate the factors influencing the treatment preferences of clinicians.
Methods: Between 2010 and 2022, the electronic medical records of adolescents between the ages of 10-18 with HMB were reviewed, and a final of 205 adolescents was included.
Transfusion History Is More Predictive Than Serum Ferritin Level in Prediction of Hypothyroidism in Transfusion Dependent Thalassemia.
Mymensingh Med J
January 2025
Dr Khaza Amirul Islam, Medical Officer (Haematology), Shaheed Ziaur Rahman Medical College Hospital, Bogra, Bangladesh; E-mail:
Transfusion dependent thalassemia (TDT) patients require a regular blood transfusion to survive. Without adequate transfusion support, they suffer many complications, and have a short life span. Near about 200 milligrams of iron remains within a single Red cell concentrate (RCC) unit.
View Article and Find Full Text PDFSevere aplastic anemia with acquired X chromosome clonality as a sole abnormality.
Ann Hematol
December 2024
Department of Medicine, Division of Hematology/Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
This case is a rare presentation of severe aplastic anemia in a 31-year-old male with acquired clonality of the X chromosome as the sole cytogenetic abnormality. This abnormality has not been reported to our knowledge, and the significance of this finding remains unclear. Comprehensive diagnostic workup included bone marrow biopsy, cytogenetic analysis, and Next-Generation sequencing, which revealed no tier I/II variants typically associated with clonal hematopoietic disorders.
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