The folate receptor as a molecular target for tumor-selective radionuclide delivery.

Nucl Med Biol

Department of Industrial and Physical Pharmacy, Purdue University, West, Lafayette, IN 47907-2091, USA.

Published: November 2003

The cell-membrane folate receptor is a potential molecular target for tumor-selective drug delivery, including radiolabeled folate-chelate conjugates for diagnostic imaging. We review here some background on the folate receptor as tumor-associated molecular target for drug delivery, and briefly survey the literature on tumor-targeting with radiolabeled folate-chelate conjugates.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0969-8051(03)00117-3DOI Listing

Publication Analysis

Top Keywords

folate receptor
12
molecular target
12
target tumor-selective
8
drug delivery
8
radiolabeled folate-chelate
8
folate-chelate conjugates
8
receptor molecular
4
tumor-selective radionuclide
4
radionuclide delivery
4
delivery cell-membrane
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!