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Intensive interdisciplinary specialized rehabilitation or regular physiotherapy for multiple sclerosis? A randomised controlled trial with economic evaluation.
Ann Phys Rehabil Med
January 2025
Physical and Rehabilitation medicine Department, Raymond Poincaré Hospital, GHU Paris Saclay, APHP, 104 Bld Raymond Poincaré, Garches, France; End: icap laboratory, Inserm Unit 1179, UVSQ, 2 Av. de la Source de la Bièvre, Montigny-le-Bretonneux, France.
Background: The benefits of Interdisciplinary Rehabilitation in an Outpatient Specialised Unit (IROSU) have not been determined.
Objectives: To compare the effects of IROSU and physiotherapy in the community on impairment, function and Quality Of Life (QoL) in people with Multiple Sclerosis (pwMS) and to determine the medico-economic impact.
Methods: Pragmatic, multicentre, parallel, randomized (centralised computer-generated randomisation) controlled trial.
Cost Effectiveness of Colorectal Cancer Screening Strategies in Middle- and High-Income Countries: A Systematic Review.
J Gastroenterol Hepatol
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Background And Aim: Colorectal cancer (CRC) is a significant global health burden, and screening can greatly reduce CRC incidence and mortality. Previous studies investigated the economic effects of CRC screening. We performed a systematic review to provide the cost-effectiveness of CRC screening strategies across countries with different income levels.
View Article and Find Full Text PDFGJFocuser: a Gaussian difference and joint learning-based autofocus method for whole slide imaging.
Biomed Opt Express
January 2025
School of Computer Science and Technology, Hainan University, Haikou 570228, China.
Whole slide imaging (WSI) provides tissue visualization at the cellular level, thereby enhancing the effectiveness of computer-aided diagnostic systems. High-precision autofocusing methods are essential for ensuring the quality of WSI. However, the accuracy of existing autofocusing techniques can be notably affected by variations in staining and sample heterogeneity, particularly without the addition of extra hardware.
View Article and Find Full Text PDFA decision-analytic method to evaluate the cost-effectiveness of remote monitoring technology for chronic depression.
Int J Technol Assess Health Care
January 2025
Department of Industrial and Systems Engineering, University of Washington, Seattle, WA, USA.
Objectives: Advances in mobile apps, remote sensing, and big data have enabled remote monitoring of mental health conditions, but the cost-effectiveness is unknown. This study proposed a systematic framework integrating computational tools and decision-analytic modeling to assess cost-effectiveness and guide emerging monitoring technologies development.
Methods: Using a novel decision-analytic Markov-cohort model, we simulated chronic depression patients' disease progression over 2 years, allowing treatment modifications at follow-up visits.
Image-based robotic (ROSA knee system) total knee arthroplasty with inverse kinematic alignment compared to conventional total knee arthroplasty : Study protocol and the inverse kinematic alignment in 8-steps using the ROSA Knee system for knee balancing technique explained.
J Orthop Surg Res
January 2025
Excellence Center for Hip & Knee Arthroplasty, Department of Orthopedic Surgery, Zuyderland Medical Center, Heerlen, The Netherlands.
Introduction: In 2020, 368 million people globally were affected by knee osteoarthritis, and prevalence is projected to increase with 74% by 2050. Relatively high rates of dissatisfactory results after total knee arthroplasty (TKA), as reported by approximately 20% of patients, may be caused by sub-optimal knee alignment and balancing. While mechanical alignment has traditionally been the goal, patient-specific alignment strategies are gaining interest.
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