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While maternal mortality decreased during the Millennium Development Goals era, it remains unacceptably high, with stagnation in reductions possible due to shocks such as COVID-19. Most women in low- and middle-income countries already receive antenatal care and over half give birth in health facilities. In cities, use of health facilities for childbirth is near universal (>90%).
View Article and Find Full Text PDFTrauma Surg Acute Care Open
January 2025
Trauma and Emergency Surgery, Chang Gung Memorial Hospital Linkou, Taoyuan, Taiwan.
Introduction: Pelvic fractures often result in life-threatening bleeding and hemodynamic instability. Resuscitative endovascular balloon occlusion of the aorta (REBOA) has emerged as a promising strategy for patients with severe pelvic fractures, facilitating subsequent hemostatic interventions. Transcatheter arterial embolization (TAE) is a well-established procedure for managing pelvic fractures accompanied by hemorrhage.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Introduction: Mycophenolate mofetil (MMF) is an immunosuppressive drug administered in the management of both autoimmune diseases and organ transplantation. The main aims of the study were: (a) to obtain information regarding the safety of using MMF in respect of its effect on normal T and B cells in lymphoid tissues; (b) to investigate whether the generation of inducible Foxp3-expressing regulatory T cells (Treg) might constitute additional mechanisms underlying the immunosuppressive properties of MMF.
Methods: The effect of MMF ( studies) and its active metabolite, mycophenolic acid, ( studies) on murine CD4 and CD8 T cells as well as B cells was determined, regarding: (a) absolute count, proliferation and apoptosis of these cells ( studies); (b) absolute count of these cells in the head and neck lymph nodes, mesenteric lymph nodes and the spleen ( studies).
Front Public Health
January 2025
Provincial Emergency Operation Center (PEOC), Government of Sindh, Karachi, Pakistan.
Introduction: Health camps are organized to provide basic health services in underprivileged communities. This study was conducted to determine community acceptance and effectiveness of health camps in the high-risk areas for the polio program in Karachi, Pakistan.
Methods: This cross-sectional survey was conducted at the health campsites in high-risk union councils (HRUCs) of four districts of Karachi, Sindh.
Surg Pract Sci
September 2022
Division of Transplant Services, Department of Surgery, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA.
Background: Liver transplantation is the gold standard treatment option for end-stage liver diseases and failure. In recent years, ex vivo liver machine perfusion has been introduced to resuscitate livers before transplantation. The RBC-based solution is the main perfusate for this matter.
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