AI Article Synopsis
- A newborn girl with neuroblastoma experienced severe hypertension, with blood pressure at 200/140 mm Hg and high active renin levels in the renal vein.
- After initial chemotherapy and two angioplasties to treat constricted renal arteries, she showed some improvement in kidney function, but blood pressure remained elevated.
- Following radical surgery to remove the neuroblastoma and the right kidney at 8 months old, her blood pressure returned to normal, marking her as one of the youngest documented cases of renovascular hypertension associated with neuroblastoma.
Article Abstract
A newborn girl with neuroblastoma presented with hypertension (blood pressure 200/140 mm Hg). The concentration of active renin in the ipsilateral renal vein was exceedingly high compared with those in the other venous systems, and angiography results showed narrowing of the contralateral 2 renal arteries. The tumor regressed in size after chemotherapy, but the blood pressure remained high. Percutaneous transluminal angioplasty (PTA) for the left renal arteries was performed twice, the first one at 5 months of age, which achieved some success in the recovery of impaired kidney function. At 8 months of age, she underwent radical resection of the neuroblastoma and removal of the right kidney, and the blood pressure promptly returned to normal postoperatively. The current patient represents the second youngest, well-documented case of renovascular hypertension with neuroblastoma in early infancy.
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| http://dx.doi.org/10.1016/j.jpedsurg.2003.09.033 | DOI Listing |
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