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http://dx.doi.org/10.1016/j.jtcvs.2003.04.002 | DOI Listing |
Sci Rep
January 2025
State Key Laboratory of Water Resources Engineering and Management, Wuhan University, Wuhan, 430,072, China.
Coordinating the downstream ecological demand and the power generation demand of hydropower stations is an important task in the operation of reservoirs, and how to evaluate the ecological satisfaction of the scheduling process is a difficult problem that needs to be solved urgently. A multi-objective optimal reservoir scheduling model was constructed to coordinate the spawning flow demand of " Four Major Chinese Carps"; The model takes the maximum power generation and the maximum membership degree of downstream river ecological water demand as the objective functions, and uses the dynamic programming multi-objective solution algorithm based on penalty factors to solve the problem, and obtains the non-inferior solution set in each scenario. The multilayer entropy-weighted TOPSIS method was used to study the non-inferior solution of the multi-objective scheduling model of the Three Gorges Reservoir, and the satisfactory solution ranking of the river flow rise process, ecological flow-related requirements, and power generation water requirements was obtained under the four schemes including 4d ~ 7d, which improved the reliability of the evaluation results and made up for the shortcomings of the traditional TOPSIS method in terms of hierarchy and weight science.
View Article and Find Full Text PDFMol Oncol
January 2025
Division of Oncology, Department of Medicine I, Medical University of Vienna, Austria.
Late-line treatment in metastatic colorectal cancer (mCRC) can improve prognosis. However, not every patient has a benefit and may experience severe side effects. Thus, predictive/prognostic biomarkers are urgently needed.
View Article and Find Full Text PDFJ Chin Med Assoc
January 2025
Division of Transplantation Surgery, Department of Surgery, Taipei Veterans General Hospital, Taiwan, ROC.
Background: ABO-incompatible liver transplantation (ABOi LT) can now be successfully performed with standard pretransplant induction therapy. For patients with chronic end-stage liver disease (ESLD), ABOi LT can achieve long-term outcomes comparable to those of blood type-compatible (ABOc) LT. Outcomes of patients with acute liver failure (ALF) who undergo urgent transplantation surgery with a limited induction period should be further investigated.
View Article and Find Full Text PDFFront Immunol
January 2025
College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.
Introduction: Animal influenza viruses pose a danger to the general public. Eurasian avian-like H1N1 (EA H1N1) viruses have recently infected humans in several different countries and are often found in pigs in China, indicating that they have the potential to cause a pandemic. Therefore, there is an urgent need to develop a potent vaccine against EA H1N1.
View Article and Find Full Text PDFChemMedChem
January 2025
Zelinsky Institute of Organic Chemistry RAS: FGBUN Institut organiceskoj himii imeni N D Zelinskogo Rossijskoj akademii nauk, Organic Chemistry, RUSSIAN FEDERATION.
For decades quaternary ammonium compounds (QACs) have served as main component of a top antiseptic and disinfectant compositions. Among them, bis-QACs are the most prominent and effective class of biocides. Although mono-QACs still dominate the antiseptic market, their activity against Gram-negative bacteria is largely inferior to bis-QACs.
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