Preparation and evaluation of sulfur-containing metal chelators.

Org Biomol Chem

Karolinska Institute, Center for Nutrition and Toxicology, Novum Research Park, SE-141 57 Huddinge, Sweden.

Published: December 2003

With a view to probe the structure and function of G-protein coupled receptors the synthesis of functionalized 8-mercaptoquinoline derivatives and 2-(2-pyridyl)thiophenol was achieved. A fluorescence-based method for determining the affinity of these metal chelators toward zinc ions was developed.

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http://dx.doi.org/10.1039/b307399hDOI Listing

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