We sought a simple and accurate method to monitor neonatal hydrocephalic infants using standard computed tomographic scans. Volume measurements were made by means of pixel counting using a personal computer and a drawing device, as a graphic tablet system, over computed tomographic scans of six infants with neonatal hydrocephalus and four age-matched control infants. The mean value (763.9 +/- 83.3 cm(3)) of the volume of the cranium in the hydrocephalic group was two times higher than that in the age-matched control infants (360.4 +/- 41.4 cm(3)), P < 0.00001. Sequential changes of the ventricular/intracranial volume ratio steadily decreased after cerebrospinal fluid diversion by means of a "two-step procedure" as early in postnatal life as feasible. The mean value (0.67 +/- 0.12) of the lateral ventricle/intracranial volume ratio at birth improved to 12 months of age (0.26 +/- 0.14), P < 0.05. This study has documented, by means of quantitative analysis of serial scans, a statistically significant increase in the neonatal hydrocephalic brain volume after cerebrospinal fluid shunting.
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http://dx.doi.org/10.1016/s0887-8994(03)00401-6 | DOI Listing |
Phys Med Biol
January 2025
Department of Radiology, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA, Chicago, 60637, UNITED STATES.
Objective: Accurate image reconstruction from data with truncation in X-ray computed tomography (CT) remains a topic of research interest; and the works reported previously in the literature focus largely on reconstructing an image only within the scanning field-of-view (FOV). We develop algorithms to invert the data model with truncation for accurate image reconstruction within the entire subject support or a region slightly smaller than the subject support.
Methods: We formulate image reconstruction from data with truncation as an optimization program, which includes hybrid constraints on image total variation (TV) and image L1-norm for effectively suppressing truncation artifacts.
Transl Stroke Res
January 2025
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4 Ring West Road, Beijing, 100070, Fengtai District, China.
Microcirculatory dysfunction is an important pathophysiology mechanism of early brain injury after aneurysmal subarachnoid hemorrhage (aSAH), which contributes to poor outcomes. The study was performed in Beijing Tiantan Hospital from October 2020 to July 2023. Patients with aSAH who underwent computed tomographic perfusion (CTP) within 24 h after ictus were enrolled prospectively.
View Article and Find Full Text PDFFront Vet Sci
December 2024
Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Introduction: Computational fluid dynamics (CFD) is gaining momentum as a useful mechanism for analyzing obstructive disorders and surgeries in humans and warrants further development for application in equine surgery. While advancements in procedures continue, much remains unknown about the specific impact that different surgeries have on obstructive airway disorders. The objective of this study was to apply CFD analysis to an equine head inhalation model replicating recurrent laryngeal neuropathy (RLN) and four surgical procedures.
View Article and Find Full Text PDFNeurocrit Care
January 2025
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, China.
Background: Microcirculatory dysfunction is one of the most important pathophysiology mechanisms of global cerebral edema (GCE) after aneurysmal subarachnoid hemorrhage (aSAH). Data regarding the impact of microcirculatory dysfunction on persistent GCE following aSAH are currently lacking. The aim of our study was to investigate whether microcirculatory dysfunction is correlated with persistent GCE in patients with aSAH across different age groups.
View Article and Find Full Text PDFFoods
December 2024
Zootechnics Department, Federal Rural University of Pernambuco (UFRPE), Recife 52171-900, PE, Brazil.
The egg has natural barriers that prevent microbiological contamination and promote food safety. The use of non-destructive methods to obtain morphometric measurements of chicken eggs has the potential to replace traditional invasive techniques, offering greater efficiency and accuracy. This paper aims to demonstrate that estimates derived from non-invasive approaches, such as 3D computed tomography (CT) image analysis, can be comparable to conventional destructive methods.
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