The anticancer drug (R,S)-biscaltamide was prepared in three steps in >90% overall yield. A key step in the new synthesis involved a new nucleophilic aromatic substitution reaction of methacrylamide anion.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1021/jo035377c | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!