The secret life of ACE2 as a receptor for the SARS virus.

Cell

Human Immunovirology and Computational Biology Group, LECB, CCR, NCI-Frederick, NIH, Frederick, MD 21702, USA.

Published: December 2003

The membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ACE2) is an essential regulator of heart function. Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133233PMC
http://dx.doi.org/10.1016/s0092-8674(03)00976-0DOI Listing

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