LacCer/CDw17 is the most abundant GSL in neutrophils. The cell-surface and intracellular presence of LacCer was determined quantitatively using anti-CDw17 mAbs in a flow cytometry assay. The quantified alterations in the level of CDw17 antigen expression are consistent with alterations in LacCer content, determined chemically. Our results show that CDw17 antigen expression defines successive stages in the maturation of the myeloid cell. The assessment of cell-surface and intracellular CDw17 expression may be useful in evaluating neutrophil physiological status.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
cell-surface intracellular
8
cdw17 antigen
8
antigen expression
8
quantitative analysis
4
analysis laccer/cdw17
4
laccer/cdw17 human
4
human myelogenous
4
myelogenous leukaemic
4
leukaemic cells
4
cells laccer/cdw17
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!