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Impact of Virtual Reality Task-Oriented Training on Upper Extremity Motor Function in Children With Cerebral Palsy: A Randomised Controlled Trial.
Pediatr Neurol
December 2024
Orthopedics Research Center, Mashhad University of Medical Science, Mashhad, Iran.
Background: This study aims to investigate the effect of a newly developed virtual reality task-oriented training (VR-TOT) video game on upper extremity fine motor function compared with conventional occupational therapy through leap motion in children with spastic hemiplegic cerebral palsy (CP).
Methods: In this double-blind randomized clinical trial, 30 children with spastic hemiplegic CP aged six to 10 years were included and randomly allocated into two groups. During six weeks, 15 patients in the intervention group received VR_TOT-based video game in addition to conventional occupational therapy, whereas 15 patients in the control group received only conventional occupational therapy.
Modulating cell-free DNA biology as the next frontier in liquid biopsies.
Trends Cell Biol
December 2024
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Technical advances over the past two decades have enabled robust detection of cell-free DNA (cfDNA) in biological samples. Yet, higher clinical sensitivity is required to realize the full potential of liquid biopsies. This opinion article argues that to overcome current limitations, the abundance of informative cfDNA molecules - such as circulating tumor DNA (ctDNA) - collected in a sample needs to increase.
View Article and Find Full Text PDF[Correlation between serum ghrelin and liver-expressed antimicrobial peptide-2 with idiopathic short stature in children].
Zhongguo Dang Dai Er Ke Za Zhi
December 2024
Department of Pediatrics, First Affiliated Hospital of Shihezi University, Shihezi, Xinjiang 832008, China.
Objectives: To investigate the expression levels of ghrelin and liver-expressed antimicrobial peptide-2 (LEAP-2) in children with idiopathic short stature (ISS) to provide reference for further understanding the etiology of short stature.
Methods: A prospective study was conducted from December 2021 to October 2023, involving 46 children diagnosed with ISS (ISS group) and 46 healthy children with normal height (control group) at the First Affiliated Hospital of Shihezi University. General data and serum levels of ghrelin and LEAP-2 were compared between the two groups.
Look before you leap: Are increased recycling efforts accelerating microplastic pollution?
J Ind Ecol
December 2024
Group for Sustainability and Technology ETH Zurich Zurich Switzerland.
To fight plastic pollution and reach net-zero ambitions, policy and industry set goals to increase the recycling of plastics and the recycled content in products. While this ideally reduces demand for virgin material, it also increases pressure on recyclers to find suitable endmarkets for the recyclate. This may lead to two effects: a multiplication of recycled content in applications already made of plastic and a substitution of non-plastic materials with cheap, low-quality recyclate.
View Article and Find Full Text PDF[Carbon Peak and Carbon Neutrality Scenarios for Key Industries in Jiangsu Province Based on LEAP Model].
Huan Jing Ke Xue
January 2025
School of Energy and Mechanical Engineering, Nanjing Normal University, Nanjing 210046, China.
In this study, strategies for meeting the carbon peak and carbon neutral targets are developed through an in-depth analysis of future energy demand and carbon emission scenarios in Jiangsu Province. The LEAP model was used to forecast energy demand and carbon emissions under different scenarios from 2021 to 2060. Under the baseline scenario, the energy demand of key industries in Jiangsu Province showed a high rate of growth, with energy consumption increasing by 2.
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