AI Article Synopsis
- - The study aimed to explore how electrical signals are transmitted from the left to right atrium in patients experiencing paroxysmal atrial fibrillation (AF).
- - Researchers mapped the right atrium of 16 patients, finding that a consistent breakthrough in electrical activity occurred near the coronary sinus (CS) entrance, with specific timing measurements noted for activations.
- - The findings suggest that the CS ostium is a key area for transseptal conduction in AF, which could be important for surgical or catheter-based treatments aimed at disrupting this pathway to manage AF.
Article Abstract
Objective: To delineate the electrophysiological properties of transseptal conduction from the left to the right atrium in patients with paroxysmal atrial fibrillation (AF).
Design And Results: Right atrial mapping using the electroanatomic mapping technique was performed at 111 +/- 16 sites in 16 patients with paroxysmal AF during pacing from distal coronary sinus (CS). A single transseptal breakthrough near the CS ostium was observed in all patients. The activation time from the pacing site to the earliest septal activation site was 47 +/- 13 ms. The total septal activation time (68 +/- 16 ms) was markedly longer but the total right atrial activation time (118 +/- 17 ms) was similar to that in patients without AF in a previous observation.
Conclusion: During distal CS pacing, a preferential site of transseptal conduction near the CS ostium was demonstrated in patients with paroxysmal AF. This has clinical implications when surgical dissection or catheter ablation is considered to eliminate interatrial connection in patients with AF.
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| http://dx.doi.org/10.1080/14017430310015505 | DOI Listing |
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