Spiral embolisation of a renal artery by the Gianturco method was carried out in eight patients. Our early experience with this technique is described. In seven patients it was possible to occlude arterial flow to the kidney completely, or almost completely. In one patient, faulty technique lead to an avoidable complication resulting in dislocation of the spiral into the femoral artery. The Gianturco method has advantages compared with other embolisation techniques, being simple, rapid, complete and permanent. In addition to its pre-operative and therapeutic use with renal tumours, the method can be used to abolish function in one or both kidneys.
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http://dx.doi.org/10.1055/s-0029-1230787 | DOI Listing |
Sci Rep
December 2024
IRCCS SYNLAB SDN, Via E. Gianturco 113, 80143, Naples, Italy.
Uterine corpus endometrial carcinoma (EC) is one of the most common malignancies in the female reproductive system, characterized by tumor heterogeneity at both radiological and pathological scales. Both radiomics and pathomics have the potential to assess this heterogeneity and support EC diagnosis. This study examines the correlation between radiomics features from Apparent Diffusion Coefficient (ADC) maps and post-contrast T1 (T1C) images with pathomic features from pathology images in 32 patients from the CPTAC-UCEC database.
View Article and Find Full Text PDFInt J Cardiol Heart Vasc
August 2024
Department of Radiology, Fondazione Toscana Gabriele Monasterio/CNR, Pisa, Italy.
Background And Aims: Cardiac ParaGangliomas (PGLs) are rare extra-adrenal tumours that arise from chromaffin cells of the sympathetic ganglia. PGL are often diagnosed incidentally, with no symptoms or symptoms related to cardiovascular dysfunction.
Methods: Cardiac Computed Tomography (CCT) and Cardiac Magnetic Resonance (CMR) can detect the correct morphology and position of the lesion and provide proper tissue characterization.
Comput Biol Med
September 2024
NeuroneLab - Department of Management and Innovation Systems (DISA-MIS), University of Salerno, Via Giovanni Paolo II, 132, Fisciano (SA), 84084, Italy; CNR-ISASI, Institute of Applied Sciences and Intelligent Systems "E. Caianiello", Via Campi Flegrei 34, Pozzuoli (NA), 80078, Italy.
Comput Methods Programs Biomed
September 2024
Institute for Informatics and Telematics, CNR, Via G. Moruzzi 1, Pisa, 56124, Italy.
Background And Objective: differential expression analysis is one of the most popular activities in transcriptomic studies based on next-generation sequencing technologies. In fact, differentially expressed genes (DEGs) between two conditions represent ideal prognostic and diagnostic candidate biomarkers for many pathologies. As a result, several algorithms, such as DESeq2 and edgeR, have been developed to identify DEGs.
View Article and Find Full Text PDFSci Rep
April 2024
Department of Pharmacy and Interuniversity Research Centre on Bioactive Peptides (CIRPeB) "Carlo Pedone", University of Naples "Federico II", Via D. Montesano 49, 80131, Naples, Italy.
Dexamethasone (DEX) is a synthetic analogue of cortisol commonly used for the treatment of different pathological conditions, comprising cancer, ocular disorders, and COVID-19 infection. Its clinical use is hampered by the low solubility and severe side effects due to its systemic administration. The capability of peptide-based nanosystems, like hydrogels (HGs) and nanogels (NGs), to serve as vehicles for the passive targeting of active pharmaceutical ingredients and the selective internalization into leukemic cells has here been demonstrated.
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