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Objective: To evaluate whether there is an association between maternal mental health, purchase of psychotropic drugs, socioeconomic status and major congenital anomalies in offspring.

Methods: A register-based cohort study of 6189 Finnish primiparous women who had a singleton delivery between 2009 and 2015. Data on pregnancy and delivery outcomes, psychiatric diagnosis, prescription drug purchases and offspring congenital anomalies were obtained from Finnish national registers.

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Disruptive multiple cell death pathways of bisphenol-A.

Toxicol Mech Methods

January 2025

Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, India.

Endocrine-disrupting chemicals (EDCs) significantly contribute to health issues by interfering with hormonal functions. Bisphenol A (BPA), a prominent EDC, is extensively utilized as a monomer and plasticizer in producing polycarbonate plastic and epoxy resins, making it one of the highest-demanded chemicals in commercial use. This is the major component used in plastic products, including bottles, containers, storage items, and food serving ware.

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Prenatal sonographic diagnosis of congenital heart disease (CHD) can lead to improved morbidity and mortality. However, the diagnostic accuracy of ultrasound, the sole prenatal screening tool, remains limited. Failed prenatal or early newborn detection of cyanotic CHD (CCHD) can have disastrous consequences.

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The role of lipid metabolism in cognitive impairment.

Arq Neuropsiquiatr

January 2025

Second Medical University, School of Clinical Medicine, Weifang Shandong Province, China.

Alzheimer's disease (AD), diabetic cognitive impairment (DCI), and vascular dementia (VD) are considered the most common causes of severe cognitive impairment in clinical practice. Numerous factors can influence their progression, and many studies have recently revealed that metabolic disorders play crucial roles in the progression of cognitive impairment. Mounting evidence indicate that the regulation of lipid metabolism is a major factor in maintaining brain homeostasis.

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Objective: To evaluate the quality of YouTube™ and TikTok™ videos as educational tools for patients with cleft lip and palate (CLP) as regards their care, and multidisciplinary treatment.

Methods: Videos were searched on YouTube™ and TikTok™ using four keywords. The reliability and quality of the first 60 videos for each keyword and platform were analyzed.

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