AI Article Synopsis
- * Out of 54 samples, 52% tested positive via cell culture, while 76% were positive with the in-house RT-PCR and 80% with the new Penter RT-PCR test, highlighting its higher efficacy (P = 0.003).
- * The Penter RT-PCR test is deemed reliable for diagnosing enterovirus-related meningitis and could enhance the treatment of associated neurological issues.
Article Abstract
Enterovirus (EV) detection by a new commercially available reverse transcription (RT)-PCR assay (Penter RT-PCR test) was compared with EV isolation from cell cultures and with EV detection by an in-house RT-PCR assay. Of the 54 cerebrospinal fluid specimens collected during a summer outbreak of aseptic meningitis, 52% were positive by cell culture versus 76% by in-house RT-PCR assay and 80% by the new RT-PCR test (52 versus 76 versus 80%; P = 0.003). This new reliable EV RNA detection test is suitable for clinical diagnosis of EV-related meningitis and may improve the management of EV-related neurological syndromes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC309008 | PMC |
| http://dx.doi.org/10.1128/JCM.41.12.5726-5728.2003 | DOI Listing |
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