Isolation of a bradykinin-potentiating factor from scorpion Tityus serrulatus venom.

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Department of Biochemistry, Butantan Institute, Sao Paulo, Brasil.

Published: January 1993

A bradykinin-potentiating factor was isolated and characterized from the scorpion Tityus serrulatus venom by chromatographic techniques and reverse phase followed by biological assays. This factor showed to be able to potentiate the contractile activity of the isolated guinea-pig ileum, inhibited the angiotensin-converting enzyme and potentiated the bradykinin-induced lowering of the arterial blood pressure in the rat.

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http://dx.doi.org/10.1007/978-3-0348-7321-5_58DOI Listing

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