The auditory apparatus of two strains of mices with normal audition is compared to that of two substrains with genetic auditory impairment. Audiometry by auditory evoked potentials at the inferior collicular level indicates complete deafness for one substrain and a 40-48 dB S.P.L. hearing loss at all frequencies for the other. Scanning and transmission electron microscopy demonstrate hair impairment of the external hair cells and degeneration of the chondriosome for the two deaf substrains.
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