[Etiology of infectious diseases in the central nervous system].

Hunan Yi Ke Da Xue Xue Bao

Department of Microbiology, Xiangya School of Medicine, Central South University, Changsha 410078, China.

Published: August 2003

Objective: To determine the etiological characteristics of infectious diseases in the central neural system (CNS).

Methods: The serum and cerebral spinal fluid of acute patients in the CNS were detected for virus-specific IgM, IgG and pathogens with enzyme-linked immunosorbent assay as well as traditional bacterial and fungal culture.

Results: Of the 823 patients, 126 (15.3%) patients were positive herpes simplex virus (HSV)-specific IgM and/or IgG, of which the maximum morbidity was under 10 years; 10(1.2%) were positive cytomegalovirus specific IgM and/or IgG; 8 (0.97%) were positive varicella-zoster virus specific IgM and/or IgG; 7 (0.85%) were diagnosed as tubercular meningitis; 6 (0.72%) as cryptocococes meningitis and 1 (0.12%) as meningococcic meningitis.

Conclusion: Viruses, especially herpes simplex viruses are the common causative agents of infectious diseases of the CNS, in which mycobacterium tuberculosis and cryptocococcus neoformans are conspicuous.

Download full-text PDF

Source

Publication Analysis

Top Keywords

infectious diseases
12
igm and/or
12
and/or igg
12
diseases central
8
herpes simplex
8
specific igm
8
[etiology infectious
4
central nervous
4
nervous system]
4
system] objective
4

Similar Publications

Evaluation of nationwide analysis surveillance for methicillin-resistant within Genomic Medicine Sweden.

Microb Genom

January 2025

Department of Laboratory Medicine, Clinical Microbiology, Faculty of Medicine and Health, rebro University, rebro, Sweden.

National epidemiological investigations of microbial infections greatly benefit from the increased information gained by whole-genome sequencing (WGS) in combination with standardized approaches for data sharing and analysis. To evaluate the quality and accuracy of WGS data generated by different laboratories but analysed by joint pipelines to reach a national surveillance approach. A national methicillin-resistant (MRSA) collection of 20 strains was distributed to nine participating laboratories that performed in-house procedures for WGS.

View Article and Find Full Text PDF

Background: Understanding based on up-to-date data on the burden of non-communicable diseases (NCDs) is limited, especially regarding how subtypes contribute to the overall NCD burden and the attributable risk factors across locations and subtypes. We aimed to report the global, regional, and national burden of NCDs, subtypes, and attributable risk factors in 2021, and trends from 1990 to 2021 by age, sex, and socio-demographic index (SDI).

Materials And Methods: We used data from the Global Burden of Disease Study 2021 to estimate the prevalence, deaths, and disability-adjusted life years (DALYs) for NCDs and subtypes, along with attributable risk factors.

View Article and Find Full Text PDF

Severity and Long-Term Mortality of COVID-19, Influenza, and Respiratory Syncytial Virus.

JAMA Intern Med

January 2025

Research and Development, Veterans Affairs Puget Sound Health Care System, Seattle, Washington.

Importance: SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) contribute to many hospitalizations and deaths each year. Understanding relative disease severity can help to inform vaccination guidance.

Objective: To compare disease severity of COVID-19, influenza, and RSV among US veterans.

View Article and Find Full Text PDF

Importance: Pediatric peripheral intravenous catheter (PIVC) insertion can be difficult and time-consuming, frequently requiring multiple insertion attempts and often resulting in increased anxiety, distress, and treatment avoidance among children and their families. Ultrasound-guided PIVC insertion is a superior alternative to standard technique (palpation and visualization) in high-risk patients.

Objective: To compare first-time insertion success of PIVCs inserted with ultrasound guidance compared with standard technique (palpation and visualization) across all risk categories in the general pediatric hospital population.

View Article and Find Full Text PDF

Nonantibiotic strategies are urgently needed to treat acute drug-resistant bacterial pneumonia. Recently, nanomaterial-mediated bacterial cuproptosis has arisen widespread interest due to its superiority against antibiotic resistance. However, it may also cause indiscriminate and irreversible damage to healthy cells.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!