Primary structures of wheat prolamins contain repetitive domains involved in the mechanical properties of gluten. In order to experience the ability of recombinant strictly periodic polypeptides, modelled on a consensus sequence of wheat gliadins (PQQPY)(8) and (PQQPY)(17) (SPR8 and SPR17 polypeptides, respectively), to be formulated in film solutions, their heterologous expression conditions, in batch culture and low cell densities, were optimized to match the high requirements of this process. A convenient and general purification procedure was also devised. Moreover, FTIR-ATR characterizations indicated that these periodic polypeptides prepared as hydrated doughy state and dried have the tendency to form a protein network through intermolecular beta-sheets, strongly maintained by hydrogen bonds. Accordingly, these recombinant polypeptides are assumed to be a suitable candidate for potential application.
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http://dx.doi.org/10.1016/j.bbrc.2003.11.028 | DOI Listing |
Front Pharmacol
January 2025
Department of Pharmacy, Cheeloo College of Medicine, The Hospital of Shandong University, Shandong University, Jinan, Shandong, China.
Background: Compound schizonepeta fumigation lotion is a type of Chinese patent medicine for external use. It has the effect of dispelling wind, eliminating dampness, reducing swelling, and relieving pain. Clinically, it is used for anal fumigation and treatment of external hemorrhoids, anal fissures, and other diseases.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Orthopaedics and Traumatology, University of Health Sciences, Adana City Training and Research Hospital, Adana, Turkey.
Background: Avascular necrosis (AVN) of the femoral head is a degenerative condition characterized by ischemic bone death, resulting in pain and impaired mobility. Core decompression, a surgical intervention, is widely performed for stage II AVN to alleviate symptoms and delay disease progression. While clinical and radiological outcomes are well-documented, the psychosocial dimensions of recovery remain underexplored.
View Article and Find Full Text PDFProc Biol Sci
January 2025
Swiss Ornithological Institute, Sempach, Switzerland.
The main features of long-distance migration are derived from landbirds breeding in the Northern Hemisphere. Little is known about migration within the tropics, presumably because tropical species typically move opportunistically and over shorter distances. However, such generalizations are weakened by a lack of solid data on spatial, temporal and behavioural patterns of intra-tropical migrations.
View Article and Find Full Text PDFBMC Public Health
January 2025
College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates.
Background: The improper disposal of unwanted or unused medications is a pressing issue that can lead to drug misuse and environmental contamination. Pharmacists play a crucial role in promoting safe drug disposal by the public. This study explores pharmacists' perceptions of the causes of unwanted and unused medications, their practices, and the barriers to promoting safe medication disposal among the public in the United Arab Emirates.
View Article and Find Full Text PDFBone Jt Open
January 2025
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Aims: The aim of this study was to report long-term clinical outcomes of a modern convertible metal-backed glenoid (MBG) in total shoulder arthroplasty (TSA).
Methods: After a minimum of 15 years, a previously studied cohort of 35 patients who received a modern convertible MBG during the period 1996 to 2005 was contacted for clinical and radiological follow-up. At last follow-up, patients were evaluated radiologically and clinically according to the Constant Score, Simple Shoulder Test, and visual analogue scale for pain.
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