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[Thyroid nodules with calcification and thyroid carcinoma]. | LitMetric

[Thyroid nodules with calcification and thyroid carcinoma].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao

Department of General Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.

Published: October 2003

Objective: To investigate the significance of thyroid calcification for diagnosis of thyroid carcinoma.

Methods: Retrospective analysis of 817 thyroid nodules' pre-operative ultrasonic and postoperative pathologic results.

Results: Total ultrasonic thyroid calcification ratio was 18.1% (148/817). Total pathologic thyroid calcification ratio was 19.6% (160/817), which in benign samples was lower than that in malignant samples (13.1% vs 53.5%, P < 0.01). Micro-calcification ratio in benign samples was lower than that in malignant samples (2.9% vs 38.6%, P < 0.01).

Conclusions: Thyroid nodules with calcification especially micro-calcification is considered to be the most specific sign of thyroid carcinoma, so the detection of it should be an important diagnostic criterion.

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