The purpose of the current study was to review the results of total knee replacement (TKR) in patients with diabetes mellitus and to test the hypothesis that patients with diabetes achieve inferior results after TKR. From a consecutive series of 5220 primary cemented TKRs, 363 were done in 291 patients with diabetes mellitus. Cefuoxime-impregnated cement was used routinely. The results in the study group were compared with the results in the patients without diabetes who had TKR during the same period. The followup averaged 52 months. Knee scores were higher in patients with diabetes preoperatively (47 versus 38) and postoperatively up to 7 years (80 versus 75). The average preoperative and postoperative pain scores also were higher in patients with diabetes. Four deep infections (1.2%) occurred in patients with diabetes versus 35 deep infections (0.7%) in patients without diabetes. The revision rate (including infections) was greater in patients with diabetes (3.6% versus 0.4 %). Knee and pain scores were similar in patients with insulin-dependent and noninsulin-dependent diabetes. Postoperative function scores, however, were lower in patients with insulin-dependent diabetes. In the study group, all deep infections occurred in patients with insulin-dependent diabetes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/01.blo.0000093002.90435.56 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Simplified Approach to Managing Newly Diagnosed Patients with Mild-to-Moderate Hypertension in Routine Clinical Practice.
Adv Ther
December 2024
Global Medical and Patient Affairs, Servier, Suresnes, France.
Introduction: The aim of the observational SIMPLE study was to assess real-life effectiveness and safety of a single-pill combination (SPC) of perindopril arginine/amlodipine in a broad range of subjects with newly diagnosed mild-to-moderate hypertension treated in Canadian general practice.
Methods: Treatment-naïve participants aged 18-65 years with mild-to-moderate hypertension, whose physicians decided to initiate the perindopril/amlodipine SPC, were recruited from Canadian clinical practice from October 2017 to February 2019. Participants were followed at 3- (M3) and 6-month (M6) visits after treatment initiation.
A Podcast on Patient and Physician Perspectives in the Holistic Care of Heart-Related Challenges of Type 2 Diabetes.
Diabetes Ther
December 2024
Patient Author, Heart Sistas, North Lauderdale, FL, USA.
Type 2 diabetes (T2D) frequently coexists with cardiorenal complications. Therefore, a holistic approach to patient management is required, with specialists such as primary care physicians, cardiologists, endocrinologists, and nephrologists working together to provide patient care. Although glycemic control is important in the management of T2D, patients with T2D and acceptable glycemic control are still at risk from cardiovascular (CV) events such as stroke, heart attack, and heart failure (HF).
View Article and Find Full Text PDFDietary and lifestyle oxidative balance score was negatively associated with the risk of diabetic kidney disease: NHANES 2005-2020.
Acta Diabetol
December 2024
Department of Endocrinology, General Hospital of Central Theater Command, Wuhan, Hubei, People's Republic of China.
Aims: There is a potential association between oxidative stress and the development of diabetic kidney disease (DKD). The Oxidative Balance Score (OBS), derived from dietary and lifestyle factors, acts as a comprehensive marker of oxidative stress. Research examining the relationship between OBS and DKD is scarce.
View Article and Find Full Text PDFAntidiabetic potency of glimepiride and naringin: an and investigation.
J Biomol Struct Dyn
December 2024
School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Bhubaneswar, India.
Glimepiride (GLM) is one of the potential antidiabetic drugs used in clinics for a long time. It is currently used in combination with metformin along with other drugs, but has shown various complications in patients from long-term use. Thus, the hypothesis is to use a lower dose of GLM with a non-toxic class of flavonoid, naringin (NARN), for better therapy with minimal side-effects.
View Article and Find Full Text PDFClinical and histopathological evaluation of patients with endometrial cancer in a University Hospital: Seven-year experience.
Malays J Pathol
December 2024
Universiti Sains Malaysia, School of Medical Sciences, Department of Obstetrics & Gynaecology, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
Introduction: Endometrial cancer is one of the leading gynaecological malignancies in developed countries and becoming more prevalent in Malaysia. These have significant impact in women and management of this disease. If it occurs on young women, and as a whole becomes a burden on the national economy and world.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!