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The Preliminary Results of a Modified Von Langenbeck Cleft Palate Repair With Tension-free Mucoperiosteal Flap Near Nasal Cavity Without Relaxation Incision.
J Craniofac Surg
December 2024
Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, & People's Hospital of Morin Dawa Daur Autonomous Banner, Inner Mongolia Autonomous Region, People's Republic of China.
To explore the application of modified Von Langenbeck cleft palate repair with tension-free mucoperiosteal flap near the nasal cavity and without relaxation incision, and the cleft palate defect was repaired by covering both sides of the edge of the in situ mucoperiosteal flap. This treatment method provides a good aesthetic restoration effect. Modified Von Langenbeck cleft palate repair with mucoperiosteal flap near the nasal cavity without tension and relaxation incision was used to repair the cleft palate.
View Article and Find Full Text PDFProfileplasty: Comprehensive Facial Profile Management Algorithm Based on 426 Patients.
J Craniofac Surg
December 2024
Private Practice, Guilford, CT.
Objective: Profileplasty traditionally involves improving a nasal hump or an underprojected chin. However, this procedure can correct other facial defects like saddle nose or prognathism. To establish the best overall profile, the nose, the midface, and the chin should be considered altogether.
View Article and Find Full Text PDFDivergent changes in social stress-induced motivation in male and female mice.
Physiol Behav
December 2024
Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington, USA. Electronic address:
Exposure to stressors has been shown to dysregulate motivated behaviors in a bidirectional manner over time. The relationship between stress and motivation is relevant to psychological disorders, including depression, binge eating, and substance abuse; however, this relationship is not well characterized, especially in females, despite their increased risk of these disorders. Social defeat stress is a common model to study stress-induced motivation changes, however, historically this model excluded females due to lack of female-to-female aggression and unreliable male-to-female aggression.
View Article and Find Full Text PDFTargeted thermosensitive liposomes loaded with gold nanoparticles and temozolomide hexadecanoate for the synergistic photothermal-chemotherapy treatment of glioblastoma.
J Pharm Sci
December 2024
Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, School of Pharmacy, Yantai University, Yantai, Shandong 264005, PR China.
Glioblastoma (GBM) is a highly aggressive malignant brain tumour which presents a significant challenge due to the limited effectiveness of current surgical and chemotherapeutic approaches. In this study, we have developed TMZ16e and gold nanoparticles coencapsulated thermosensitive liposomes modified with anti-EphA3 (anti-EphA3-TMZ16e-GNPs-TSL) delivered via the intranasal route to achieve photothermal chemotherapy (PCT) for improving the therapeutic effects of GBM. The prepared anti-EphA3-TMZ16e-GNPs-TSL were spherical with a particle size of 173.
View Article and Find Full Text PDFMultiple primary brain abscesses in a 14 years old immunocompetent boy: A tale of Proteus mirabilis infestation from Pakistan.
Pak J Med Sci
December 2024
Muhammad Talha Bilal, Post Graduate Resident, Department of Neurosurgery, Unit-I, Punjab Institute of Neurosciences, Lahore, Pakistan.
Brain abscess (BA) formation that may be due to due to Gram-positive bacteria commonly and less commonly due Gram-negative bacteria affects pediatric population. Most cases are secondary to the involvement of ear, nose, throat and sinuses (ENTS). We describe a rare case of a 14 year old patient presenting with generalized tonic clonic seizures for the last six months associated with fever, vomiting and headache.
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