Unlabelled: The success of cell salvage varies depending upon how many shed red blood cells (RBC) are captured from the surgical wound and returned to the patient. Here, the authors hypothesized that pneumatic disk (PD) processing might provide better RBC recovery when compared with traditional Latham bowl (LB) techniques. Comparison of the speed of processing, product hemoglobin and salvage efficiency was made between the two machines when their reservoirs were loaded with blood volumes ranging from 100 mL to 1000 mL. The PD provided a consistent hemoglobin concentration (21.7 +/- 0.8 g/dL; mean +/- SD), whereas the LB provided varying hemoglobin concentrations dependent upon the starting volume (range, 2.9 +/- 0.7 g/dL to 18.4 +/- 0.8 g/dL). The PD also provided more efficiency versus full LB only (79.4% versus 56.3%; P = 0.001). When all RBCs were processed, the LB technology provided statistically larger degrees of RBC return (79.4% versus 83.6% for the PD versus LB, respectively; P < 0.001). The processing speed of the LB was faster at all starting volumes. In conclusion, for small volumes of blood loss where a full LB is not achieved, the PD will return a larger number of cells with a more consistent hemoglobin per volume of blood processed.
Implications: This study compared two types of cell salvage equipment. Pneumatic disk processing may offer advantages over traditional devices when small blood loss is anticipated.
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http://dx.doi.org/10.1213/01.ANE.0000087047.90881.F2 | DOI Listing |
Trials were inconsistent while reporting findings on the benefits of the intermittent regimen. Recent conclusive evidence to show overall effect was limited. This review compared intermittent and daily iron folic acid supplementation (IFAS) on pregnancy outcomes.
View Article and Find Full Text PDFRev Med Interne
January 2025
Service de médecine interne, centre national de référence des syndromes drépanocytaires majeurs de l'adulte, hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75015 Paris, France; Inserm U1163, laboratoire « Mécanismes cellulaires et moléculaires des désordres hématologiques et implications thérapeutiques », institut Imagine, université Paris-Cité, 75015 Paris, France; Laboratoire d'Excellence GR-Ex, 75015 Paris, France; Faculté de santé, université Paris-Cité, 75006 Paris, France. Electronic address:
Introduction: Extramedullary hematopoiesis (EMH) is very rarely described during sickle cell disease (SCD). Our aim was to describe six cases of EMH occurring in adult SCD patients and to conduct a literature review.
Methods: Retrospective, descriptive, and monocentric study, identifying all cases of EMH recorded in our cohort of adult SCD patients, up to April 2024.
ESMO Open
January 2025
Department of Onco-hematology, Hematology Unit, Azienda Ospedaliera Annunziata, Cosenza, Italy; Department of Pharmacy, Health and Nutritional Science, University of Calabria, Rende, Italy. Electronic address:
Background: Daratumumab-refractory multiple myeloma (Dara-R MM) presents a significant treatment challenge. This study aimed to evaluate the efficacy and survival outcomes of elotuzumab, pomalidomide, and dexamethasone (EloPd) in a large, real-world cohort of patients with Dara-R MM, with particular focus on progression-free survival (PFS) and overall survival (OS).
Materials And Methods: This retrospective analysis included 247 Dara-R MM patients treated with EloPd.
Clin Nephrol Case Stud
December 2024
Nephrology Center and the Okinaka Memorial Institute for Medical Research.
A 47-year-old woman with a 12-year history of anemia and high C-reactive protein (CRP) levels was admitted to our hospital with worsening fatigue and night sweats. She had high levels of immunoglobulin G (IgG; 4182 mg/dL), IgA (630.6 mg/dL), and CRP (7.
View Article and Find Full Text PDFBiol Trace Elem Res
January 2025
Programa de Pós-Graduação em Zootecnia, Universidade Federal da Bahia, Av. Adhemar de Barros, s/n, Ondina, Salvador, 40170-110, BA, Brazil.
The study aimed to examine the interaction between diets supplemented with zinc-L-selenomethionine (ZnSeMet) and two stocking densities (SD) on Nile tilapia (Oreochromis niloticus) males. Four extruded diets were formulated: 0.0, 0.
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