Based on over 50,000 parental descriptors of children gathered in eight different countries, we used a combination of focus group sorting of descriptors in each country and factor analyses of instruments developed in four of the countries (United States, China, Greece, and the Netherlands) to describe children ages 3 to 12 years to select items for an instrument that would work well across countries to access personality. Through many factor analyses of indigenous items in each country, a core set of 141 items was used in three of the countries, with over 3000 parents responding to our instruments in China, Greece, and the United States. Much cross-comparative research analysis has resulted in 15 robust midlevel scales that describe the structures of parental descriptors that are common to the three countries. The data on the English (U.S.) sample are presented in detail. Links to temperament and behavior problems are presented and discussed.
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http://dx.doi.org/10.1111/1467-6494.7106005 | DOI Listing |
Front Pharmacol
December 2024
Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Background: Gliclazide, a second-generation sulfonylurea derivative still widely used as a second-line treatment for type 2 diabetes mellitus, is well known to be subject to interindividual differences in bioavailability, leading to variations in therapeutic responses among patients. Distinct gut microbiota profiles among individuals are one of the most crucial yet commonly overlooked factors contributing to the variable bioavailability of numerous drugs. In light of the shift towards a more patient-centered approach in diabetes treatment, this study aimed to conduct a pharmacoinformatic analysis of gliclazide metabolites produced by gut microbiota and assess their docking potential with the SUR1 receptor to identify compounds with improved pharmacological profiles compared to the parent drug.
View Article and Find Full Text PDFJ Phys Condens Matter
December 2024
Center for Computing Research, Sandia National Laboratories, Albuquerque, NM 87185, United States of America.
A new method is presented to generate atomic structures that reproduce the essential characteristics of arbitrary material systems, phases, or ensembles. Previous methods allow one to reproduce the essential characteristics (e.g.
View Article and Find Full Text PDFDev Cogn Neurosci
October 2024
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, 760 Westwood Plaza, Los Angeles, CA 90024, United States.
This editorial focuses on the issue of data misuse which is increasingly evidenced in social media as well as some premiere scientific journals. This issue is of critical importance to open science projects in general, and ABCD in particular, given the broad array of biological, behavioral and environmental information collected on this American sample of 12.000 youth and parents.
View Article and Find Full Text PDFInt J Environ Res Public Health
October 2024
Heroes in Mind Advocacy and Research Consortium (HiMARC), Edmonton, AB T6G 2G4, Canada.
: There is international agreement that military families (MFs)-active service members, reservists, veterans, and their families-must be resilient to overcome military life adversities. Resilience is defined either as skillsets or as processes implicating multi-systems in a socio-ecological context. While research on resilience-building specific to children and families who face adversity is growing, there is a paucity of evidence on MF-centred resilience-building.
View Article and Find Full Text PDFCad Saude Publica
October 2024
Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Vitória da Conquista, Brasil.
Accidents in childhood have a high morbidity and mortality rate and are often preventable, which reinforces the importance of educational measures to prevent unintentional injuries. This study aimed to identify and describe useful educational strategies for preventing childhood accidents in communities. This systematic review was guided by PRISMA (2020) and registered on the PROSPERO platform (ID: CRD42024500956).
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