Unlabelled: A wealth of bioinformatics tools and databases has been created over the last decade and most are freely available to the general public. However, these valuable resources live a shadow existence compared to experimental results and methods that are widely published in journals and relatively easily found through publication databases such as PubMed. For the general scientist as well as bioinformaticists, these tools can deliver great value to the design and analysis of biological and medical experiments, but there is no inventory presenting an up-to-date and easily searchable index of all these resources. To remedy this, the BioWareDB search engine has been created. BioWareDB is an extensive and current catalog of software and databases of relevance to researchers in the fields of biology and medicine, and presently consists of 2800 validated entries.
Availability: BioWareDB is freely available over the Internet at http://www.biowaredb.org/
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http://dx.doi.org/10.1093/bioinformatics/btg306 | DOI Listing |
JMIR Hum Factors
January 2025
Institute of General Practice, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Background: The internet is a key source of health information, but the quality of content from popular search engines varies, posing challenges for users-especially those with low health or digital health literacy. To address this, the "tala-med" search engine was developed in 2020 to provide access to high-quality, evidence-based content. It prioritizes German health websites based on trustworthiness, recency, user-friendliness, and comprehensibility, offering category-based filters while ensuring privacy by avoiding data collection and advertisements.
View Article and Find Full Text PDFJMIR Public Health Surveill
January 2025
Division of Global HIV and TB, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, 30322, United States, 1 8103383534.
Background: Population size estimation (PSE) for key populations is needed to inform HIV programming and policy.
Objective: This study aimed to examine the utility of applying a recently proposed method using Google Trend (GT) internet search data to generate PSE (Google Trends Population Size Estimate [GTPSE]) for men who have sex with men (MSM) in 54 countries in Africa, Asia, the Americas, and Europe.
Methods: We examined GT relative search volumes (representing the relative internet search frequency of specific search terms) for "porn" and, as a comparator term, "gay porn" for the year 2020.
J Proteome Res
January 2025
Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, 69120 Heidelberg, Germany.
The first step in bottom-up proteomics is the assignment of measured fragmentation mass spectra to peptide sequences, also known as peptide spectrum matches. In recent years novel algorithms have pushed the assignment to new heights; unfortunately, different algorithms come with different strengths and weaknesses and choosing the appropriate algorithm poses a challenge for the user. Here we introduce PeptideForest, a semisupervised machine learning approach that integrates the assignments of multiple algorithms to train a random forest classifier to alleviate that issue.
View Article and Find Full Text PDFRadiology
January 2025
From the Institute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany.
Background Studies have explored the application of multimodal large language models (LLMs) in radiologic differential diagnosis. Yet, how different multimodal input combinations affect diagnostic performance is not well understood. Purpose To evaluate the impact of varying multimodal input elements on the accuracy of OpenAI's GPT-4 with vision (GPT-4V)-based brain MRI differential diagnosis.
View Article and Find Full Text PDFJMIR Dermatol
January 2025
NYU Langone Health, 550 1st Ave, New York, NY, 10016, United States, 1 (212) 263-5290.
Background: Lipomas are benign tumors composed of encapsulated adipocytes. Although relatively common, uncertainty remains about the population-level prevalence, the etiology, and the degree of public interest in lipomas and associated removal procedures.
Objective: The spatiotemporal patterns of public interest in lipomas and lipoma removal procedures were characterized.
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