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The ruptured sinus of Valsalva aneurysm (RSOV), a rare but well-recognized clinical entity, is invariably a form of left-to-right shunt due to rupture into right-sided chambers. It causes profound hemodynamic effects, especially when the rupture is acute. Like most other left-to-right shunts, it was only a matter of time before this rare defect also became amenable to transcatheter closure (TCC).

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: Kawasaki disease (KD) is a systemic vasculitis of medium arteries, particularly involving coronary arteries. Coronary artery lesions (CALs) is the most serious complication in the acute stage, potentially leading to ischemic cardiomyopathy, myocardial infarction and sudden death. Environmental factors and genetic background contribute to individual susceptibility to develop CALs.

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Dissecting aneurysm of sinus of Valsalva into interventricular septum and rupturing into left ventricle through multiple sinuses: a rare case report.

Eur Heart J Case Rep

August 2024

Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC), Civil Hospital Campus, Asarwa, Ahmedabad 380016, Gujarat, India.

Article Synopsis
  • Ruptured sinus of Valsalva (RSOV) is a rare heart condition mainly affecting the right coronary sinus or the non-coronary sinus, typically resulting in ruptures into right-sided heart chambers.
  • A 24-year-old male patient exhibited symptoms like fatigue and chest pain, with diagnostic imaging revealing multiple sinus of Valsalva aneurysms affecting both the right and left coronary sinuses, necessitating successful surgical repair.
  • The involvement of multiple sinuses and ruptures into the interventricular septum are very rare, with significant risks like complete heart block and sudden death, highlighting the importance of thorough diagnostic methods and timely treatment.
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Aortic valve aneurysm, an extremely rare complication secondary to infective endocarditis (IE), may cause heart failure due to rupture of the aneurysm. Coronavirus disease 2019 (COVID-19) has been reported to cause cardiovascular complications and alter susceptibility to secondary infections such as IE. Herein, we report a case of IE with a fatal outcome caused by rupture of an aortic valve aneurysm in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive autopsy case.

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