Microwave-assisted synthesis utilizing supported reagents: a rapid and efficient acylation procedure.

Org Lett

High-Throughput Organic Synthesis Group, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064-6113, USA.

Published: November 2003

[reaction: see text] The application of microwave heating to a polymer-assisted solution-phase (PASP) synthesis technique has been utilized to develop a rapid and efficient protocol for the solution-phase synthesis of amides from either amine or carboxylic acid cores.

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Source
http://dx.doi.org/10.1021/ol0358915DOI Listing

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