AI Article Synopsis
- p23 is a crucial cochaperone that supports the Hsp90 chaperone pathway, helping in the binding of client proteins.
- It functions at a later stage of the Hsp90 cycle, improving the maturation of these client proteins.
- Recent research indicates that p23 might have other roles in the cell that need to be investigated further.
Article Abstract
p23 is a small but important cochaperone for the Hsp90 chaperoning pathway. It appears to facilitate the adenosine triphosphate-driven cycle of Hsp90 binding to client proteins. It enters at a late stage of the cycle and enhances the maturation of client proteins. Although this role of p23 is fairly well established, recent studies suggest that it may have additional functions in the cell that merit further exploration.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514861 | PMC |
| http://dx.doi.org/10.1379/1466-1268(2003)008<0108:paspwc>2.0.co;2 | DOI Listing |
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