AI Article Synopsis

  • A multiinstitutional study investigated the formation of adhesions to expanded polytetrafluoroethylene (ePTFE) mesh used in laparoscopic ventral incisional hernia repair.
  • Retrospective assessments by nine surgeons showed that 91% of 65 patients experienced no or only minimal adhesions (scores of 0 or 1), with no severe adhesions observed.
  • The study underscored the need for further comparative analyses of newer materials used in intraabdominal mesh placement, given the generally favorable adhesion outcomes seen with ePTFE mesh.

Article Abstract

Objectives: Laparoscopic ventral incisional hernia repair involves intraabdominal placement of a synthetic mesh, and the possibility of formation of severe visceral adhesions to the prosthesis is a principal concern. Little clinical information based on reoperative findings is available about adhesions to biomaterials placed intraabdominally. We conducted a multiinstitutional study of adhesions to implanted expanded polytetrafluoroethylene (ePTFE) mesh at reoperation in patients who had previously undergone laparoscopic incisional hernia repair done with the same mesh implantation technique.

Methods: Nine surgeons retrospectively assessed the severity of adhesions to ePTFE mesh at reoperation in 65 patients. For each case, adhesions were assigned a score of 0 to 3, with 0 indicating no adhesions and 3 severe adhesions.

Results: The mean time from mesh implantation to reoperation was 420 days (range, 2 to 1739 days). No adhesions were observed in 15 cases. Forty-four cases received an adhesion score of 1, and 6 cases a score of 2; no scores of 3 were assigned. Thus, 59 patients (91%) had either no or filmy, avascular adhesions. No enterotomies occurred during adhesiolysis.

Conclusions: In this large series of reoperations after laparoscopic incisional hernia repair, no or minimal formation of adhesions to implanted ePTFE mesh was observed in 91% of cases, and no severe cohesive adhesions were found. Comparative analyses of newer materials based on clinical reoperative findings are warranted to assess the safety of intraabdominally placed meshes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021335PMC

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