Solitary fibrous tumors show a classic morphologic pattern ("patternless pattern") consisting mainly of a proliferation of bland spindle cells with varying amounts of thick, often hyalinized or keloid-like, intercellular collagen bundles. Immunohistochemistry shows a strong reactivity for CD34 antigen, vimentin, and, in a variable percentage, bcl-2 antigen. We report the case of a 50-year-old man with a large solitary fibrous tumor located in the pelvic cavity with a rare nonspecific histologic pattern of pseudovascular formations. The patient underwent pelvic exenteration with orthotopic continent urinary diversion and sigmoid-J-pouch bowel reconstruction. No signs of tumor recurrence were noted within 24 months of surgery.
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http://dx.doi.org/10.1016/s0090-4295(03)00695-2 | DOI Listing |
Med J Armed Forces India
December 2024
Senior Resident (Respiratory Medicine), Dr DY Patil Medical College, Hospital & Research Centre, Dr DY Patil Vidyapeeth University, Pune, India.
Solitary fibrous tumors of pleura (SFTP) are rare neoplasms derived from mesenchymal cells of the pleura. A 63-year-old male patient, laborer by profession, presented with progressive dry cough and breathlessness for one month. Clinically he had left-sided intrathoracic mass which was confirmed by CT thorax.
View Article and Find Full Text PDFDermatopathology (Basel)
November 2024
Department of Dermatology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Spindle cell lipoma (SCL) is a benign adipocytic tumor usually found in the subcutis of the posterior neck, upper back, and shoulder, predominantly in middle-aged males. This case report describes an atypical presentation of SCL in a 26-year-old male with a history of malignant melanoma. The patient presented with an erythematous plaque with central hyperpigmentation on the right upper arm, an uncommon location and presentation for SCL.
View Article and Find Full Text PDFAm J Surg Pathol
December 2024
Department of Pathology, Indiana University School of Medicine, Indianapolis, IN.
Juxtaglomerular cell tumor (JxGCT) is a rare type of renal neoplasm demonstrating morphologic overlap with some mesenchymal tumors such as glomus tumor (GT) and solitary fibrous tumor (SFT). Its oncogenic drivers remain elusive, and only a few cases have been analyzed with modern molecular techniques. In prior studies, loss of chromosomes 9 and 11 appeared to be recurrent.
View Article and Find Full Text PDFCureus
November 2024
Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, JPN.
Introduction: The ZAP-X® Gyroscopic Radiosurgery System (ZAP Surgical Systems, Inc., San Carlos, CA, USA) is expected to be a highly accurate next-generation treatment system that enables gyro-stereotactic irradiation of intracranial lesions. In this study, we report the initial treatment course using ZAP-X for intracranial lesions that recurred after Gamma Knife (GK) treatment.
View Article and Find Full Text PDFPak J Med Sci
December 2024
Dr. Zubair Ahmad Khan, MBBS, FCPS Neurosurgery Consultant Neurosurgeon, Department of Neurosurgery Unit III, Punjab Institute of Neurosciences, Lahore, Pakistan.
Lipofibromatosis is a rare benign soft tissue tumor that primarily affects children. There is limited cytological description and management of this rare condition in the literature which leads to misdiagnosis. The two years old patient first presented with a big, non-tender swelling on the scalp's right temporoparietal area.
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