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Multimodality Imaging Evaluation of Diseases of the Pulmonic Valve and Right Ventricular Outflow Tract for the Adult Cardiologist.
Circ Cardiovasc Imaging
January 2025
Division of Cardiology, Massachusetts General Hospital, Boston. (S.P.M., A.T.-R., A.C.S.S., S.H., C.P.L., T.W.C., D.F.Y., E.Y.).
Disorders of the pulmonic valve (PV) receive considerably less attention than other forms of valvular heart disease. Due to the dramatically improved survival of children with congenital heart disease over the last 5 decades, there has been a steady increase in the prevalence of adults with congenital heart disease, which necessitates that clinicians become familiar with the anatomy and the evaluation of right ventricular outflow tract and PV anomalies. A multimodality imaging approach using echocardiography, cardiac computed tomography, and magnetic resonance imaging is essential for a comprehensive evaluation of the anatomy and function of the right ventricular outflow tract, PV, and supravalvular region.
View Article and Find Full Text PDFTemporal change in cardiac function and clinical indices in adults with valvular pulmonic stenosis.
Int J Cardiol Congenit Heart Dis
March 2024
From the Department of Cardiovascular Medicine, Mayo Clinic Rochester, MN, 55905, USA.
Background: Patients with palliated pulmonary valve stenosis (PVS) have less cardiac remodeling and symptoms as compared to patients with repaired tetralogy of Fallot (TOF) presenting with similar severity of right ventricular outflow tract (RVOT) disease. What is not known is whether patients with PVS versus TOF presenting with similar severity of RVOT disease at baseline, would have similar (or different) pace of cardiac remodeling and disease progression over time. The study objective was to compare temporal changes in clinical and cardiac function indices between adults with palliated PVS and repaired TOF presenting with moderate/severe RVOT disease.
View Article and Find Full Text PDFPrenatal detection of novel compound heterozygous variants of the gene in a fetus with congenital heart disease.
Front Genet
November 2024
Department of Obstetrics and Gynaecology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Background: Congenital heart disease (CHD) is the most common birth defect and heart valve defects are the most common cardiac defect, accounting for over 25% of all congenital heart diseases. To date, more than 400 genes have been linked to CHD, the genetic analysis of CHD cases is crucial for both clinical management and etiological determination. Patients with autosomal-recessive variants of are predisposed to Cardiac Valvular Dysplasia-1 (CVDP1), which predominantly affects the right-sided heart valves, including the pulmonic, tricuspid, and mitral valves.
View Article and Find Full Text PDFIdentifying the Severity of Heart Valve Stenosis and Regurgitation Among a Diverse Population Within an Integrated Health Care System: Natural Language Processing Approach.
JMIR Cardio
September 2024
Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, United States.
Article Synopsis
- - The study focused on improving the identification of valvular heart disease (VHD), specifically stenosis and regurgitation in aortic, mitral, tricuspid, and pulmonic valves, using a natural language processing (NLP) algorithm applied to transthoracic echocardiography (TTE) reports from a large healthcare system.
- - Researchers analyzed over a million TTE reports from Kaiser Permanente Southern California between 2011 and 2022, revealing significant prevalence rates of various valve lesions, with mitral regurgitation being the most common condition identified.
- - The study highlighted the challenge of relying on administrative diagnostic codes, emphasizing the potential of NLP to accurately capture and assess VHD cases by evaluating
Myxoma Involving the Pulmonary Valve - A Case Report of an Atypical Cardiac Tumor, Treated Using an Unusual Approach.
Eur J Case Rep Intern Med
May 2024
Allegheny General Hospital, Pittsburgh, USA.
Background: Atypical myxoma has been reported in various locations in the heart, however, myxoma involving the pulmonary valve is rare. Here we present a case of pulmonic valve myxoma which was resected via a percutaneous approach.
Case Report: A 66-year-old female with known metastatic adenocarcinoma of the lung, and chronic obstructive pulmonary disease presented with acute onset shortness of breath for two days.
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