Fas-ligand mediated apoptosis in severe sepsis and shock.

Scand J Infect Dis

Division of Surgical Research, Department of Surgery, Brown University School of Medicine, Rhode Island Hospital, Providence, RI 02903, USA.

Published: December 2003

Alterations in the apoptotic process in lymphoid tissues is a common condition which is encountered in the severely septic animal and critically ill patient. Here we attempt to delineate the pathological significance of these apoptotic changes and the role of Fas-FasL mediated contribution to this process.

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