Introduction: Breast cancer is the most common neoplasm among women, with a peak incidence at an age between 40 and 60. The contemporary guidelines for prophylactic breast cancer screening emphasize on performing an annual mammography, starting at the age of 40.

Objective: To analyze the results of the prophylactic mammography and clinical examination in a group of climacteric women before initiation of HRT.

Material And Methods: 108 women were screened for a period of 12 months. The average age of participants was 51.4 +/- 3.67 years.

Results: In two patients in the absence of evidence for breast cancer from the clinical exam the mammogram was evaluated as indicative for breast neoplasm. In both of the cases the diagnosis was confirmed hystologically.

Discussion: The results from the selected group of patients represents a 2% incidence of breast cancer, unrecognized by the clinical exam. The mammography proves its high effectiveness and the recommendation for timely prophylactic mammography referring the climacteric women is in concordance with the latest world standards for breast cancer screening.

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