Introduction: Bone morphogenetic protein (BMP) has been shown to induce bone formation and union in long bone defects and nonunions. There are, however, no previous reports of BMP being used for ulnar nonunions. We report on five cases of resistant ulnar nonunions treated with a composite implant consisting of a biocoral frame, collagen carrier, and bovine BMP.
Materials And Methods: Four diaphyseal and one olecranon ulnar nonunions were treated using BMP/coral implant combined with internal fixation. Additional autografting was used in three cases. All of the cases were challenging in their own ways: Three of the patients had been operated on earlier for their nonunion without success, one had a 40 mm bone loss, and one had a 9-month-old untreated olecranon fracture. After excision of the sclerotic surfaces of the nonunion, the gap was filled with autograft and a composite implant containing BMP. Fixation was done with a compression plate in the diaphyseal nonunions and with a tension band in the olecranon nonunion.
Results: Solid union was achieved in all five cases. No infections or other adverse effects were encountered.
Conclusion: These preliminary results suggest that BMP-containing implants might be a feasible alternative or superior to autografting in the treatment of resistant ulnar nonunions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00402-003-0599-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Application of elbow skin fold extension line in extreme elbow flexion in ulnar Kirschner wire insertion of extended supracondylar humeral fractures in children].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
January 2025
Department of Orthopedics, Nanjing Drum Tower Hospital Group Suqian Hospital, the Affiliated Suqian Hospital of Xuzhou Medical University, Suqian Jiangsu, 223800, P. R. China.
Objective: To discuss the elbow skin fold extension line in Kirschner wire internal fixation of extended supracondylar humeral fractures in children.
Methods: The clinical data of 58 children with extended supracondylar fractures of the humerus who met the selection criteria between August 2021 and July 2024 were retrospectively analyzed. In 28 cases, needle placement of medial epicondyle of humerus was performed with the assistance of the elbow skin fold extension line (study group), and 30 cases were assisted by routine touch of the medial epicondyle of the humerus (control group).
3-dimensional investigation of the vascular anatomy of the triquetrum with micro-computed tomography.
Ann Anat
January 2025
Department of Anatomy, Ankara University School of Medicine, Ankara, Turkey. Electronic address:
Background: This study aims to demonstrate the 3-dimensional pattern of the nutrient vessels of the triquetrum using micro-computed tomography and determine the safe region for screw applications to the bone.
Methods: Seven fresh frozen cadavers' ulnar and radial arteries were injected with Microfil MV-117. Triquetral bones were dissected and examined using micro-computed tomography.
Comparative Outcomes Between Three Different Techniques in the Fixation of Ulnar Styloid Fractures.
Handchir Mikrochir Plast Chir
January 2025
Hand Surgery, Baltalimani Special Hospital for Bone Diseases, Istanbul, Turkey.
Purpose: This study aims to compare the clinical and radiological outcomes of three different techniques used in the surgical treatment of ulnar styloid fractures.
Material And Method: Ulnar styloid fractures treated surgically between 2012 and 2022 were evaluated retrospectively. There were three groups in the study: Group I (Kirschner wire, N= 19), Group II (tension band, N= 27) and Group III (headless compression screw, N= 25).
Posterior interosseous artery distal ulna graft for management of radius nonunion: Technique and case report.
J Hand Microsurg
March 2025
Division of Hand Surgery, Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ, USA.
Distal radius fracture nonunion can result in significant deformity, loss of function, and chronic pain. Presented here is a case of distal radius nonunion that was surgically reconstructed with a pedicled distal ulna bone graft based on the periosteal branches of the posterior interosseus artery (PIA). This technique has limited prior utilization for adult distal radius nonunion treatment but offers an effective option for surgical reconstruction of distal radius nonunion with preservation of the radiocarpal joint, utilizing a less invasive surgery that also reduces hospitalization stay.
View Article and Find Full Text PDFTemporary circular external fixation for effective management of bilateral radial non-union in a Toy Poodle.
Open Vet J
November 2024
Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.
Background: Distal radius fractures are prevalent in small and toy-breed dogs, presenting significant treatment challenges due to complications such as delayed union or non-union. These complications are often exacerbated by reduced vascular density at the distal diaphyseal-metaphyseal junction of the radius, which is vital for bone healing, particularly in toy and small breed dogs. Circular external fixation (CEF) is known for its effectiveness in managing acute and chronic fractures and providing temporary stabilization in humans.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!