Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1046/j.1537-2995.2003.00583.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Article Synopsis
- - A delayed hemolytic transfusion reaction (DHTR) can occur in sickle cell disease (SCD) patients after receiving blood transfusions, leading to serious anemia weeks later due to immune responses to foreign red blood cell antigens.
- - The case study describes a pediatric SCD patient who experienced DHTR after her second transfusion, emphasizing the importance of extending RBC antigen profiling through molecular genotyping instead of just serology.
- - Molecular genotyping offers better accuracy in matching blood types, which can help prevent complications during transfusions and improve management by quickly identifying rare donors when needed.
Pre-transfusion Testing Using Crossmatching Agglutination Reaction Grades Combined With Rh Subgroup Phenotyping in Patients With Autoantibodies: A Three-year Experience at a Tertiary Hospital.
Ann Lab Med
September 2023
Department of Laboratory Medicine, Pusan National University School of Medicine, Yangsan, Korea.
Background: The currently recommended pre-transfusion testing techniques for patients with autoantibodies are complex, time-consuming, and labor-intensive. Therefore, although the red blood cell (RBC) selection method using crossmatched RBC agglutination reaction grades (i.e.
View Article and Find Full Text PDFClinical and immunohematological characterization of autoimmune hemolytic anemia in children.
Transfus Apher Sci
June 2023
Department of Transfusion Medicine, Apollo Multispeciality Hospitals, Kolkata 700054, India.
Autoimmune Hemolytic Anemia (AIHA) in childhood is uncommon and estimated to be three per million annually under 18 years of age. Detailed immunohematological and clinical characterizations are essential for correct diagnosis of the disease and its management. In this study we described AIHA in children with regards to patient demography, underlying etiology, disease classification, antibody characterization, clinical features, degree of in vivo hemolysis and transfusion management.
View Article and Find Full Text PDFHyperhemolysis in a patient with sickle cell disease and recent SARS-CoV-2 infection, with complex auto- and alloantibody work-up, successfully treated with tocilizumab.
Transfusion
July 2022
Department of Pathology, University of Chicago, Chicago, Illinois, USA.
Background: Hyperhemolysis syndrome (HHS) is a severe delayed hemolytic transfusion reaction seen in sickle cell disease (SCD) patients, characterized by destruction of donor and recipient RBCs. It results in a drop in hemoglobin to below pretransfusion levels and frequently reticulocytopenia.
Case Report: We report a case of a man in his thirties with SCD with a recent hospitalization 2 weeks prior for COVID-19.
Blood group discrepancy in mixed-type autoimmune hemolytic anemia in a pediatric patient.
Asian J Transfus Sci
November 2021
Department of Transfusion Medicine and Blood Bank, AIIMS, Raipur, Chhattisgarh, India.
Autoimmune hemolytic anemia (AIHA) is characterized by the presence of antibodies directed against self-antigens on red blood cells (RBCs) leading to progressive RBC destruction along with reduced red cell survival. Mixed-type AIHA is characterized by the presence of both warm and cold-autoantibodies. These autoantibodies may cause blood-group discrepancy or cross-match incompatibility leading to delay in arranging suitable blood unit for transfusion.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!