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Varicella zoster meningoencephalitis without exanthem: immunocompetent host.
J Pak Med Assoc
December 2024
Department of Anaesthesiology, Aga Khan University Hospital, Karachi, Pakistan.
In an immunocompetent person, varicella zoster virus (VZV) is an uncommon cause of aseptic meningoencephalitis. Reactivation of the latent varicella zoster virus from nerve infection results in shingles, a condition marked by rash, intense pain, and dermal involvement in immunocompromised hosts. We present an unusual case of a 22-year-old immunocompetent male diagnosed as VZV meningoencephalitis without exanthem.
View Article and Find Full Text PDFOpportunistic Infections, Mortality Risk, and Prevention Strategies in Patients With Vacuoles, E1 Enzyme, X-Linked, Autoinflammatory, Somatic (VEXAS) Syndrome.
Open Forum Infect Dis
July 2024
National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Article Synopsis
- VEXAS syndrome is a genetic disorder that causes bone marrow failure and systemic inflammation, which can lead to a higher risk of infections for affected patients.
- In a study of 94 patients with VEXAS, 6% developed pneumonia (PJP), 15% experienced reactivation of the alphaherpesvirus, and 10% had non-tuberculous mycobacterial infections.
- The research found that developing PJP or NTM significantly increases the risk of death, while prophylactic treatments for these infections were shown to be highly effective in reducing infection rates.
M2 Genotype of virus associated with Severe Herpes zoster in Pakistan.
Pak J Med Sci
July 2024
Prof. Dr. Rani Faryal, Ph.D., Postdoc Department of Microbiology, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
This case report is of herpes zoster which is caused by Varicella zoster virus (VZV). The patient was presented with acute renal failure associated with intravenous acyclovir administration for its management. A 50 years old man visited the hospital with rashes on his back.
View Article and Find Full Text PDFThe Incidence of Herpes Zoster Complications: A Systematic Literature Review.
Infect Dis Ther
July 2024
Pallas Health Research & Consultancy, a P95 Company, Rotterdam, Netherlands.
Introduction: The objective of this work was to summarize the incidence of herpes zoster (HZ) complications in different populations.
Methods: Systematic literature review of PubMed, Embase, and Virtual Health Library records between January 1, 2002 and October 20, 2022 using search strings for HZ, complications, and frequency measurements.
Results: The review included 124 studies, most conducted in the general population (n = 93) and on individuals with comorbidities (n = 41) ≥ 18 years of age.
Herpes Zoster Ophthalmicus Secondary to Periorbital Cellulitis.
Cureus
May 2024
Internal Medicine, Garnet Health Medical Center, Middletown, USA.
Article Synopsis
- * The initial symptoms include a blistering rash, fever, headache, and fatigue, generally resolving with supportive care.
- * A case study highlights a 54-year-old woman with a rare form of VZV, known as herpes zoster ophthalmicus (HZO), which is an unusual manifestation of the virus.
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