The "crazy-paving" pattern is a common finding at thin-section computed tomography (CT) of the lungs. It consists of scattered or diffuse ground-glass attenuation with superimposed interlobular septal thickening and intralobular lines. This finding has a variety of causes, including infectious, neoplastic, idiopathic, inhalational, and sanguineous disorders. Specific disorders that can cause the crazy-paving pattern include Pneumocystis carinii pneumonia, mucinous bronchioloalveolar carcinoma, pulmonary alveolar proteinosis, sarcoidosis, nonspecific interstitial pneumonia, organizing pneumonia, exogenous lipoid pneumonia, adult respiratory distress syndrome, and pulmonary hemorrhage syndromes. Knowledge of the many causes of this pattern can be useful in preventing diagnostic errors. In addition, although the causes of this pattern are frequently indistinguishable at radiologic evaluation, differences in the location of the characteristic attenuation in the lungs, as well as the presence of additional radiologic findings, the patient's history, and the clinical presentation, can often be useful in suggesting the appropriate diagnosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1148/rg.236035101 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical approach for pulmonary alveolar proteinosis in children.
World J Clin Cases
October 2024
Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Article Synopsis
- - Pulmonary alveolar proteinosis (PAP) is a rare lung condition marked by excessive surfactant buildup in the alveoli and is classified into four categories: primary, secondary, congenital, and unclassified.
- - The primary form is linked to issues with the GM-CSF receptor, with autoimmune and hereditary subtypes, while secondary PAP arises from various conditions affecting macrophages, and congenital PAP is caused by genetic mutations.
- - Diagnosis involves specific imaging features and bronchoalveolar lavage, while treatment typically includes whole lung lavage alongside targeted therapies depending on the underlying cause.
Bacillus megaterium infection presenting as pulmonary alveolar proteinosis, a case report.
BMC Infect Dis
August 2024
Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifuyuan Street, Dongcheng District, Beijing, 100730, China.
Article Synopsis
- Pulmonary alveolar proteinosis (PAP) is usually linked to autoimmune disorders, but this case highlights a rare instance caused by an infection from Bacillus megaterium.
- A 58-year-old woman experienced cough and breathing difficulties for six months, with a CT scan revealing a distinctive "crazy paving" pattern, and B. megaterium was identified through a biopsy.
- This case is significant as it’s the first documented instance of PAP caused by B. megaterium in otherwise healthy individuals, emphasizing the need to consider unusual infections as potential secondary causes of PAP.
Case Report: The first reported case of pulmonary alveolar proteinosis with myasthenia gravis in a 27-year-old patient.
F1000Res
May 2024
Pneumology Department, Military Hospital of Tunis, Montfleury, Tunis, 1008, Tunisia.
Pulmonary alveolar proteinosis is a very rare diffuse lung disease characterized by the accumulation of amorphous and periodic acid Schiff-positive lipoproteinaceous material in the alveolar spaces due to impaired surfactant clearance by alveolar macrophages. Three main types were identified: Autoimmune, secondary and congenital. Pulmonary alveolar proteinosis has been previously reported to be associated with several systemic auto-immune diseases.
View Article and Find Full Text PDFPulmonary alveolar proteinosis following severe COVID - 19 infection: A case report.
Respir Med Case Rep
March 2024
Department of Critical Care and Pulmonary Medicine, Parkview Health, Fort Wayne, IN, USA.
A 67-year-old male, with a history of severe COVID-19 infection and exposure to talc was seen for worsening shortness of breath for months, requiring supplemental oxygen. He was treated for COVID-19 infection and suspected pneumonia with no improvement. His pulmonary function test (PFT) worsened and computed tomography (CT) showing bilateral airspace opacities with ground-glass opacities (GGO), also worsened over time.
View Article and Find Full Text PDFCrazy-Paving Pattern in Pulmonary Sarcoidosis.
N Engl J Med
February 2024
China-Japan Friendship Hospital, Beijing, China
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!