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In vitro evaluation of anthelmintic activity of biocompatibile carbon quantum dot nanocomposite against egg and larval stages of equine strongyles.
BMC Vet Res
January 2025
Materials Synthesis Laboratory, Carbon Tech Industrial Group, Carbon Tech, Tehran, Iran.
Background: Strongyle nematodes pose a major challenge in veterinary parasitology, causing significant economic losses in livestock due to resistance to conventional treatments. Current anthelmintics, like Ivermectin, often encounter resistance issues. This study aims to address these gaps by synthesizing Carbon Quantum Dots (CQDs) and Copper-Doped CQDs (Cu@CQDs) using glucose extract, and evaluating their nematicidal properties against strongyles in vitro.
View Article and Find Full Text PDFAssociation between nutritional status, daily nutrition delivery and clinical outcomes of critically ill adult patients admitted to the intensive care unit: a protocol for Isfahan multicentre prospective observational cohort ICU study (the Isfahan-ICU study).
BMJ Open
January 2025
Department of Clinical Nutrition,School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Introduction: There is currently limited information regarding the association between the modified Nutrition Risk in Critically Ill (mNUTRIC) score, nutrition delivery and clinical outcomes in critically ill patients admitted to the intensive care unit (ICU) section.
Methods And Analysis: The Isfahan-ICU study is a multicentre, prospective observational cohort study that will be conducted on critically ill adults treated in the trauma or medical ICU sections of six hospitals to investigate whether clinical outcomes, including length of ICU stay and 30-day survival, vary by the mNUTRIC score at admission or the 7-day nutrition delivery. This paper outlines the Isfahan-ICU study protocol approved by the ethics committee of Isfahan University of Medical Sciences, Iran.
A comparative analysis in monitoring 24-hour urinary copper in wilson disease: sampling on or off treatment?
Orphanet J Rare Dis
January 2025
Internal Medicine IV, Department of Gastroenterology, University Hospital Heidelberg, INF 410, Heidelberg, 69120, Germany.
Background & Aim: Twenty-four-hour urinary copper excretion (24 h-UCE) is the standard diagnostic tool for dose adjustments in maintenance therapy in Wilson disease (WD) patients. Guidelines lack data if both variants of 24 h-UCE measurement (with or without 48 h of treatment interruption) are equally interpretable.
Methods: Eighty-four patients with a confirmed diagnosis of WD treated with chelators (50% of patients with D-Penicillamine and 50% with trientine) and with pairwise 24-h-UCE values on-therapy and off-therapy were included in the analysis.
A novel IoT-based approach using fractional fuzzy Hamacher aggregation operators application in revolutionizing healthcare selection.
Sci Rep
January 2025
Department of Management Information Systems, Faculty of Economics and Administration, King Abdulaziz University, Jeddah, Saudi Arabia.
In the current era, IoT-based healthcare solutions play a pivotal role in transforming the healthcare landscape by addressing key challenges and significantly enhancing the quality, accessibility, and efficiency of medical services, particularly for individuals in remote areas. This paper introduces innovative operations on fractional fuzzy sets (FFS), specifically the Hamacher sum and product, and establishes corresponding operational laws. Building upon these foundations, we propose novel aggregation operators (AoPs) leveraging Hamacher norms and rigorously analyze their properties within the FFS framework.
View Article and Find Full Text PDFIntroduction: The increasing use of electronic cigarettes among young adults in Southeast Asia is concerning. This study explores the motivations and challenges faced by young adults in quitting vaping and their perceptions of current public health messages and interventions in Singapore, which has stringent antivaping laws and active public health campaigns.
Methods: A qualitative descriptive study was conducted involving in-depth interviews with 15 participants aged 18-35.
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