Aim: Subjects with symptomatic or asymptomatic peripheral arterial or cerebro-vascular disease have an increased risk of death or cardiovascular event. The aim of this study was to determine whether intima-media thickening of the common carotid artery and/or a low ankle brachial index (ABI) are related with an increased risk of cardio-vascular event after percutaneous coronary angioplasty (PTCA).
Methods: One hundred and thirteen consecutive, patients (88 males, 25 females, mean age: 62 years) undergoing PTCA were included. Intima media thickness (IMT) of the common carotid artery and ABI were measured within the 2 days following the PTCA. Subjects were followed up for 10.2 +/- 4 months. The end-point was a composite criterion associating death, non fatal acute myocardial infarction, recurrence or worsening of angina pectoris, hospitalisation for heart failure, new positive exercise stress testing.
Results: In the follow-up study a common carotid IMT >0.7 mm was a predictor of event (p=0.03) in the univariate analysis. The other risk factors were unstable angina (p=0.001) and PTCA on the left descending coronary artery (p<0.05). We did not find any relation between the end-point and ABI or presence of atheroma on the common femoral artery. In the logistic regression analysis unstable angina was associated with a 3.14 fold increased risk (IC 95%: 1.51-6.4, p=0.002), subjects without HMG-CoA inhibitors drugs at the inclusion had also an increased risk of 2.5 (IC 95%:1.09-5.75, p=0.02).
Conclusion: This study suggest that CCA-IMT is associated with an increased risk of cardiac events after PTCA. The measurement of subclinical disease could be useful for identifying high-risk patients.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Removal of microcatheter entrapped in the middle cerebral artery in a neonate via common carotid arteriotomy.
J Vasc Surg Cases Innov Tech
February 2025
Department of Vascular Surgery, Sir Charles Gairdner Hospital, Perth, Australia.
A 2-day-old neonate was referred to the vascular surgery service owing to concerns of limb perfusion after entrapment of a microcatheter in the middle cerebral artery. The catheter was inserted via the umbilical artery to treat a vein of Galen arteriovenous malformation. This catheter inadvertently became entrapped owing to device failure, was cut at the insertion site, and left in situ for 3 months.
View Article and Find Full Text PDFMoyamoya phenomenon following clipping of intracranial aneurysm: case report.
J Surg Case Rep
January 2025
Department of Neurosurgery, The Walton Centre NHS Trust, Lower Lane, Liverpool L97LJ, United Kingdom.
Subarachnoid haemorrhage from aneurysmal rupture is a common emergency in neurosurgery. Depending on aneurysm position, morphology, size, associated clot, and symptoms, it is either managed by endovascular occlusion or by clipping. Here we report the first known case of secondary Moyamoya phenomenon following the clipping of a supraclinoid internal carotid artery Aneurysm.
View Article and Find Full Text PDFInfluence of Geometric Parameters on The Hemodynamic Characteristics of The Vertebral Artery.
J Biomech Eng
January 2025
State Key Laboratory of Clean Energy Utilization, Zhejiang University, Yuquan Campus, 38 Zheda Road, Hangzhou 310027, Zhejiang, China; Shanghai Institute for Advanced Study of Zhejiang University, Zhangjiang Guochuang Center phase, No.799, Dangui Road, Shanghai 200120, China.
The carotid and vertebral arteries are principal conduits for cerebral blood supply and are common sites for atherosclerotic plaque formation. To date, there has been extensive clinical and hemodynamic reporting on carotid arteries; however, studies focusing on the hemodynamic characteristics of the vertebral artery (VA) are notably scarce. This article presents a systematic analysis of the impact of VA diameter and the angle of divergence from the subclavian artery (SA) on hemodynamic properties, facilitated by the construction of an idealized VA geometric model.
View Article and Find Full Text PDFDefining Thresholds for Meaningful Health Status Changes Following Transfemoral Carotid Artery Stenting.
Catheter Cardiovasc Interv
January 2025
Department of Internal Medicine, Vascular Medicine Outcomes Program (VAMOS), Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Background: Evaluating health status changes following transfemoral carotid artery stenting (TF-CAS) is essential for assessing procedural success, but meaningful clinical changes are unknown. We aimed to determine minimal clinically important differences (MCIDs) and quantify health status improvement or worsening rates after TF-CAS using the Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy (SAPPHIRE) registry data.
Methods: The SAPPHIRE registry included patients undergoing TF-CAS from 2010 to 2014 for both symptomatic and asymptomatic carotid stenosis.
Prevalence and risk factors of stroke in patients with non-valvular atrial fibrillation: a case-control study.
World Neurosurg
January 2025
Department of Neurology, General Hospital of Ningxia Medical University, Yinchuan, 750000, Ningxia Hui Autonomous Region, China. Electronic address:
Objective: To analyze the prevalence and influencing factors of stroke in patients with non-valvular atrial fibrillation (SIPWNVAF), and to provide a reference basis for the prevention and control of stroke.
Methods: Data were obtained from the China National Stroke Screening Survey (CNSSS). From January 2016 to December 2023, a total of 15471 permanent residents aged ≥ 40 years in Yinchuan were screened.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!