We report the first experimental violation of local realism by four-photon Greenberger-Horne-Zeilinger (GHZ) entanglement. In the experiment, the nonstatistical GHZ conflicts between quantum mechanics and local realism are confirmed, within the experimental accuracy, by four specific measurements of polarization correlations between four photons. In addition, our experimental results also demonstrate a strong violation of Mermin-Ardehali-Belinskii-Klyshko inequality by 76 standard deviations. Such a violation can only be attributed to genuine four-photon entanglement.
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