We propose a hierarchical discrete time survival model to analyse registry data on haemodialysis patients in Rio de Janeiro, Brazil, collected at different dialysis centres. Our aim is to estimate differences in hazard ratios attributable to variation in dialysis centre performance, after adjusting for further observed covariates both at the individual and centre level. The proposed model allowed for the estimation of a residual calendar time trend varying across dialysis centres through the adoption of a random slope model. These calendar time trends turned out to have significant variation, after adjustment for important observed covariates. The technique can be easily adapted to other diseases as long as survival time is the measurement of interest.
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http://dx.doi.org/10.1002/sim.1571 | DOI Listing |
PLoS One
January 2025
Faculty of Engineering, Free University of Bozen-Bolzano, Bolzano, South Tyrol, Italy.
Appraisal models, such as the Scherer's Component Process Model (CPM), represent an elegant framework for the interpretation of emotion processes, advocating for computational models that capture emotion dynamics. Today's emotion recognition research, however, typically classifies discrete qualities or categorised dimensions, neglecting the dynamic nature of emotional processes and thus limiting interpretability based on appraisal theory. In our research, we estimate emotion intensity from multiple physiological features associated to the CPM's neurophysiological component using dynamical models with the aim of bringing insights into the relationship between physiological dynamics and perceived emotion intensity.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Entomology and Plant Pathology, NC State University, Raleigh, North Carolina, United States of America.
We examined the evolutionary history of Phytophthora infestans and its close relatives in the 1c clade. We used whole genome sequence data from 69 isolates of Phytophthora species in the 1c clade and conducted a range of genomic analyses including nucleotide diversity evaluation, maximum likelihood trees, network assessment, time to most recent common ancestor and migration analysis. We consistently identified distinct and later divergence of the two Mexican Phytophthora species, P.
View Article and Find Full Text PDFArch Orthop Trauma Surg
January 2025
Department of Orthopaedics, Wright State University, 30 E Apple St., Suite 2200, Dayton, OH, 45409, USA.
Introduction: We propose and assess the biomechanical stability of medial column screw supplementation in a synthetic distal femur fracture model.
Materials And Methods: Twenty-four low density synthetic femora modeling osteoporotic, intraarticular distal femur fractures with medial metaphyseal comminution were split into two fixation groups: (1) lateral locking distal femur plate (PA- plate alone) and (2) lateral locking distal femur plate with a 6.5 mm fully threaded medial cannulated screw (PWS- plate with screw).
J Pers Med
January 2025
Section of Hygiene, Department of Health Science and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Next-generation sequencing (NGS) can explain how genetics influence morbidity and mortality in children. However, it is unclear whether health providers will perceive and use such treatments. We conducted a discrete choice experiment (DCE) to understand Italian health professionals' preferences for NGS to improve the diagnosis of paediatric genetic diseases.
View Article and Find Full Text PDFEntropy (Basel)
January 2025
School of Computer Science, Guangdong Polytechnic Normal University, Guangzhou 510665, China.
Emotion recognition is an advanced technology for understanding human behavior and psychological states, with extensive applications for mental health monitoring, human-computer interaction, and affective computing. Based on electroencephalography (EEG), the biomedical signals naturally generated by the brain, this work proposes a resource-efficient multi-entropy fusion method for classifying emotional states. First, Discrete Wavelet Transform (DWT) is applied to extract five brain rhythms, i.
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