Attenuation correction stress myocardial SPECT: possibility of reduction in number of rest investigation.

Nucl Med Rev Cent East Eur

Department of Nuclear Medicine - PET Center, Na Homolce Hospital, Prague, Czech Republic.

Published: January 2004

Background: Attenuation-corrected (AC) imaging frequently shows normal stress myocardial perfusion while non-corrected (NC) imaging shows hypoperfusion. The aim of the work was to assess whether it is necessary to continue with resting examination in this situation.

Material And Methods: 121 consecutive patients had positive finding at AC and/or NC sestamibi stress myocardial imaging using E.CAM Profile system and resting examination was carried out. AC stress imaging was normal while NC imaging showed hypoperfusion in 29 cases. In one case this finding was reversed. In this group of 30 patients with AC/NC stress discrepancies, resting examination has not revealed any additional information in 28 cases.

Results: In 2 cases NC imaging, in contrast to AC, showed stress ischaemia. In one of these 2 cases coronarography was carried out with negative result. In the other case patient refused coronarography.

Conclusions: The resting examination did not bring any benefits in 29-30 cases out of 30 (96.7 to 100.0%) patients with AC/NC stress discrepancies. If the results of this study are considered accordingly, in our group approximately one fourth of the resting examinations (29 to 30 out of 121) could be saved.

Download full-text PDF

Source

Publication Analysis

Top Keywords

resting examination
16
stress myocardial
12
imaging hypoperfusion
8
patients ac/nc
8
ac/nc stress
8
stress discrepancies
8
stress
7
imaging
6
resting
5
attenuation correction
4

Similar Publications

Aims/hypothesis: Diabetic kidney disease (DKD) features intrarenal inflammation, in which T cells play a part. Hypoxia-inducible factor-1α (HIF-1α), a key transcription factor regulating cellular responses to hypoxia, is reportedly involved in the course of inflammation. The role of HIF-1α in DKD has been investigated, but the conclusions are controversial so far.

View Article and Find Full Text PDF

Objectives: Fatigue and sleep disorders are common geriatric conditions and are associated with an increased risk of cognitive decline. This study aimed to examine the relationships among self-perceived fatigue, objective muscle fatigue, sleep apnea risk, insomnia, and cognitive function, focusing on their associations with mild cognitive impairment (MCI).

Design: Cross-sectional study.

View Article and Find Full Text PDF

Cerebral autosomal-dominant arteriopathy, subcortical infarcts, and leukoencephalopathy (CADASIL) is the most prevalent monogenic inherited cause of cerebral small-vessel disease. Despite its prevalence, there is currently no proven therapy to prevent or reverse the progression of the disease. This study aimed to characterize the functional integrity of long white matter tracts in CADASIL transgenic mice, both with and without focal white matter lesions in the corpus callosum added on, utilizing optical resting-state functional connectivity imaging alongside behavioral examinations.

View Article and Find Full Text PDF

Adolescents who have sustained a concussion or mild traumatic brain injury (mTBI) are prone to repeat injuries which may be related to subtle motor deficits persisting after clinical recovery. Cross-sectional research has found that these deficits are associated with altered functional connectivity among somatomotor, dorsal attention, and default mode networks. However, our understanding of how these brain-behavior relationships change over time after clinical recovery is limited.

View Article and Find Full Text PDF

Background: Impaired fat oxidation is linked to cardiometabolic risk. Maximal fat oxidation rate (MFO) reflects metabolic flexibility and is influenced by lean mass, muscle strength, muscle quality - defined as the ratio of strength to mass - and cardiorespiratory fitness. The relationship between these factors and fat oxidation is not fully understood.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!