The objective of this study was to produce an improved finite element (FE) model of the human middle ear and to compare the model with human data. We began with a systematic and accurate geometric modeling technique for reconstructing the middle ear from serial sections of a freshly frozen temporal bone. A geometric model of a human middle ear was constructed in a computer-aided design (CAD) environment with particular attention to geometry and microanatomy. Using the geometric model, a working FE model of the human middle ear was created using previously published material properties of middle ear components. This working FE model was finalized by a cross-calibration technique, comparing its predicted stapes footplate displacements with laser Doppler interferometry measurements from fresh temporal bones. The final FE model was shown to be reasonable in predicting the ossicular mechanics of the human middle ear.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10237-002-0014-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Morphometric evaluation of middle ear anatomical structures using full volume (12 × 9) CBCT scans: A retrospective study in Navi Mumbai.
Natl J Maxillofac Surg
November 2024
Department of Oral Medicine and Maxillofacial Radiology, Dr. G. D. Pol Foundations YMT Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Introduction: The tympanic cavity contains three tiny bones, the malleus, incus, and stapes, which have a fundamental role in the transmission of sound. Recent research emphasizes the use of CBCT for the anatomic study of the temporal bone. The information about middle ear anatomy on CBCT scans is meager; hence, this retrospective study was conducted to identify and determine the various morphometrical parameters of the malleus using CBCT which can be helpful during reconstructive procedures for the otologic surgeon.
View Article and Find Full Text PDFSerous otitis media as a cause for language delay following cleft palate repair-A case-control study.
Natl J Maxillofac Surg
November 2024
Department of ENT, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India.
Background And Objectives: Serous otitis media (SOM), also called otitis media with effusion (OME) or glue ear, is a collection of non-purulent fluid within the middle ear space. Children with cleft palate are more prone to develop this condition. This is caused by impaired eustachian tube function in cleft palate.
View Article and Find Full Text PDFSleep-Associated Traits and Hearing Difficulties in Noise: A Bidirectional Mendelian Randomization Study.
Ear Hear
January 2025
Department of Audiology & Vestibular Medicine, Senior Department of Otolaryngology-Head & Neck Surgery, the Sixth Medical Center of People's Liberation Army (PLA) General Hospital, Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing, China.
Objectives: The aim of this study was to investigate the causal relationships between sleep-associated traits and hearing difficulties in noise (HDinN) by Mendelian randomization (MR) analysis.
Design: Single nucleotide polymorphisms associated with chronotype, insomnia, sleep duration, daytime dozing or sleeping, and ease of getting up in the morning were extracted from European population genome-wide association study pooled data for bidirectional MR analysis. The MR-Egger regression, the inverse variance weighted technique, and the weighted median method were used for data analysis.
BA inhibits LPS-stimulated inflammatory response and apoptosis in human middle ear epithelial cells by regulating the Nf-Kb/Iκbα axis.
Open Life Sci
December 2024
Department of ENT, Yueqing People's Hospital, 338, Qingyuan Road, Chengnan Street, Yueqing City, Wenzhou, Zhejiang, 325600, China.
Otitis media (OM) is a prevalent childhood ear disease characterized by inflammation of the middle ear cavity, which can lead to ear pain, fever, and hearing loss. The pathogenesis of OM is multifaceted, encompassing a variety of factors including bacterial or viral infections, host immune responses, and the function of middle ear epithelial cells. Boswellic acid (BA), a natural triterpene compound extracted from frankincense resin, has been proven to possess significant anti-inflammatory and immunomodulatory effects.
View Article and Find Full Text PDFSudden sensorineural hearing loss (SSNHL) presents as the abrupt onset of hearing loss. Approximately 88% of SSNHL has no identifiable etiology and is termed idiopathic sudden sensorineural hearing loss (ISSHL). Hearing specialists have investigated ISSHL since the 1970s.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!