Introduction: Osteoporotic vertebral fractures result in increased kyphosis angle, an alteration that may lead to disturbance in physical capacity.
Objective: We sought to evaluate physical capacity and disability in a group of osteoporotic patients.
Material And Methods: Fifteen women with osteoporosis and vertebral fractures (G1), 20 women with osteoporosis without vertebral fractures (G2), and 20 control women (G3) were selected. The variables of physical capacity were measured using a treadmill. The patients spent 4 min standing quietly, 4 min walking at 3 km/h, and 10 min walking at 4 km/h. The SF-36 questionnaire was also applied.
Results: The results showed that women with osteoporosis and vertebral fractures (G1) had increased kyphosis angle (median 60 degrees ), while the angle was 43.5 degrees for G2 and 37 degrees for G3. Oxygen consumption (VO(2) (kg)), METS (metabolic equivalent), and energy expenditure (kcal/h) during the standing period were higher in G1 than in G2 (G1 vs G2, p=0.016, p=0.017, and p=0.012, respectively), whereas no difference in these parameters was observed between groups during the walking period. The energy expenditure during walking at 3 km/h and at 4 km/h showed a correlation with thoracic kyphosis in G1 (p=0.01 and p=0.017, respectively). No difference in SF-36 scores was observed between the three groups.
Conclusion: Energy expenditure showed a correlation with the angle of thoracic kyphosis. Patients with or without osteoporosis showed the same energy expenditure during the walking period. The SF-36 score was similar for the three groups.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s00198-003-1512-2 | DOI Listing |
Bone
January 2025
Research Institute, Meir Medical Center, Kfar Saba, Israel.
The objective of this retrospective, database study was to characterize the rate, magnitude and timeline of increases in parathyroid hormone (PTH) levels post-denosumab (DMAb) vs. zoledronic acid (ZA) injection in patients with osteoporosis and near normal baseline PTH. Included were osteoporotic females, ≥50 years, initiating treatment with 60 mg DMAb or 5 mg ZA.
View Article and Find Full Text PDFJ Clin Densitom
January 2025
University of Health Sciences, Umraniye Training and Research Hospital, Department of Radiology, Istanbul, Turkey.
Background: Osteoporosis, a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration, poses a significant public health challenge globally. While the gold standard for diagnosing osteoporosis is dual-energy X-ray absorptiometry (DXA), its use is limited by factors like spinal deformities and artifacts. This study aims to explore the potential of routine T1-weighted MRI sequences in predicting osteopenia and osteoporosis through the vertebral bone signal (VB) to cerebrospinal fluid signal (CSF) ratio.
View Article and Find Full Text PDFJ Cereb Blood Flow Metab
January 2025
KG Jebsen Centre for Brain Fluid Research, University of Oslo, Oslo, Norway.
A potential two-way passage of cells and substances between the brain and skull bone marrow may open for new insights into neurological disease. The arachnoid membrane was traditionally considered to restrict cells and larger molecules in CSF from entering the dura and bone marrow directly. However, new data on exchange between brain and skull bone marrow have recently emerged.
View Article and Find Full Text PDFAm J Case Rep
January 2025
Department of Orthopedic Surgery, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
BACKGROUND The management of unstable atlas fractures remains a subject of ongoing debate and controversy. The conservative surgical treatment commonly involves fusion, resulting in severe loss of cervical spine mobility, and a large incisions and extensive tissue dissection are required. We aim to introduce a novel concept and surgical approach for treating atlas fracture, one that involves minimizing trauma while maintaining mobility of the upper cervical spine without resorting to fusion.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Spinal Surgery, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing 100044, China.
: The aim of this study was to investigate the incidence of vertebral refractures following percutaneous kyphoplasty (PKP) and to explore risk factors for augmented vertebral refractures, thereby assisting spinal surgeons in clinical practice. : We analyzed the records of 495 patients with single-segment osteoporotic vertebral compression fractures (OVCFs) who were treated with single-entry PKP at our institution from March 2016 to August 2022. Univariate analysis, binary logistic regression, and ROC curve analysis were performed to determine potential risk factors, independent risk factors, and discrimination ability.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!