Fulminant sepsis described in childhood has long stimulated surgeons to attempt partial or total preservation of the spleen when possible. Persistence of splenic tissue ensures preservation of the immunological competence of the organ. Total splenectomy ought to be avoided in the first 10 years of life; in subsequent years an attempt to partially preserve the organ is to be recommended. A segmental arterial vascularization with avascular interlobar planes has been demonstrated in the spleen allowing partial resection of the organ. We report a case of a voluminous epithelial splenic cyst in a teenager removed by subtotal splenectomy.

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