High migration rate of two types of threaded acetabular cups.

Arch Orthop Trauma Surg

Orthopaedic Department, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

Published: January 2004

AI Article Synopsis

Article Abstract

Introduction: Survivorship analysis was performed on 479 Link V-type threaded cups and on 110 modified V-type Bad Bramstedt cups (a modification of the Link V-type cup since 1993 with a smaller primary coil) to evaluate the effect of the modifications.

Materials And Methods: Indication for hip arthroplasty with a Link V-type cup was an inflammatory arthritis in 310 patients, osteoarthritis in 138 patients and dysplastic hip joints in 31 patients. The average follow-up was 8.6+/-3.2 (range 3.0-15.2) years. The 110 modified V-type Bad Bramstedt cups had a mean follow-up period of 4.5+/-0.7 (range 3.0-5.9) years, including 49 with inflammatory arthritis, 49 with osteoarthritis and 12 with dysplastic hip joints. To evaluate the migration rate and radiolucent lines, radiographical examination according to the method of Nunn et al. and Delee and Charnley was performed on 264 Link V-type cups with a mean follow-up period of 8.2+/-2.7 years and 59 modified V-type Bad Bramstedt cups with a mean follow-up period of 4.6+/-0.7 years. Relevant parameters influencing cup migration were analysed.

Results: The cumulative survival rate of the former Link V-type acetabular cup was 94.5% after 5 years, 88.1% after 10 years and 70.2% after 15 years. The Bad Bramstedt cup showed a 5-year survivorship rate of 97.9%. Migration of more than 3 mm or tilting of the cup greater than 5 degrees was found in 73% of the former type and in 39% of the modified cup. Radiolucent lines greater than 2 mm and detectable in two zones appeared in 6.4% of the former Link V-type and in 1.7% of the Bad Bramstedt cup design. Among the influencing factors analysed, length of follow-up and primary cup positioning showed a significant correlation to cup migration.

Conclusion: The modification of the Link V-type cup showed no satisfactory improvement in cup migration. Therefore, both threaded cups were abandoned in favour of cementless press-fit cups.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00402-003-0592-yDOI Listing

Publication Analysis

Top Keywords

link v-type
28
bad bramstedt
20
modified v-type
12
v-type bad
12
bramstedt cups
12
cup
12
v-type cup
12
cups follow-up
12
follow-up period
12
v-type
10

Similar Publications

Animals often acquire their microbial symbionts from the environment, but the mechanisms underlying how specificity of the association is achieved are poorly understood. We demonstrate that the conserved proton pump, V-type ATPase (VHA), plays a key role in the establishment of the model light-organ symbiosis between the squid Euprymna scolopes and its bacterial partner, Vibrio fischeri. Recruitment of V.

View Article and Find Full Text PDF

Bafilomycin A1 inhibits V-type H ATPases on the molecular level, which acidifies endo-lysosomes. The main objective of the study was to assess the effect of bafilomycin A1 on Ca content, NAADP-induced Ca release, and ATPase activity in rat hepatocytes and human colon cancer samples. Chlortetracycline (CTC) was used for a quantitative measure of stored calcium in permeabilized rat hepatocytes.

View Article and Find Full Text PDF

The interdependent transport of yeast vacuole Ca and H and the role of phosphatidylinositol 3,5-bisphosphate.

J Biol Chem

December 2022

Department of Biochemistry, University of Illinois Urbana-Champaign, Urbana, Illinois, USA; Center for Biophysics & Quantitative Biology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA. Electronic address:

Yeast vacuoles are acidified by the v-type H-ATPase (V-ATPase) that is comprised of the membrane embedded V complex and the soluble cytoplasmic V complex. The assembly of the V-V holoenzyme on the vacuole is stabilized in part through interactions between the V a-subunit ortholog Vph1 and the lipid phosphatidylinositol 3,5-bisphosphate (PI(3,5)P). PI(3,5)P also affects vacuolar Ca release through the channel Yvc1 and uptake through the Ca pump Pmc1.

View Article and Find Full Text PDF

Pathogenic variants of the gene cause X-linked hypohidrotic ectodermal dysplasia (XLHED), which is characterized by structural abnormalities or lack of ectodermal appendages. Signs of dysplasia are not restricted to derivatives of the ectodermal layer, but mesodermal abnormalities, such as craniofacial dysmorphism, are also frequently observed, suggesting close reciprocal interactions between the ectoderm and mesoderm; however, a causal link has remained unsubstantiated. We investigated the functional impact of defective ectodysplasin A1 (Eda1) signaling on postnatal bone homeostasis in Eda1-deficient Tabby mice.

View Article and Find Full Text PDF

Bidirectional nutrient flow between partners is integral to the cnidarian-dinoflagellate endosymbiosis. However, our current knowledge of the transporter proteins that regulate nutrient and metabolite trafficking is nascent. Four transmembrane transporters that likely play an important role in interpartner nitrogen and carbon exchange were investigated with immunocytochemistry in the model sea anemone ("Aiptasia"; strain NZ1): ammonium transporter 1 (AMT1), V-type proton ATPase (VHA), facilitated glucose transporter member 8 (GLUT8), and aquaporin-3 (AQP3).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!