Background: Pronuclear (PN) zygote morphology has been proposed as a useful tool for selecting the best embryos for transfer.

Methods: PN morphology was recorded in 888 zygotes and classified according to similar/different PN size [groups A (n = 816) and B (n = 72)] and to the number, distribution and synchrony of nucleolar precursor bodies (NPB): subgroup I, pronuclei with 3-4 polarized NPB; subgroup II, 5-7 synchronic polarized NPB or 7-10 NPB distributed randomly; and subgroup III, morphologies other than those of groups I or II. Embryo development and chromosomal abnormalities were evaluated for each PN pattern.

Results: In patients aged 37 years, statistical differences among groups were not observed.

Conclusions: In patients aged 37 years, this correlation does not exist.

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http://dx.doi.org/10.1093/humrep/deg458DOI Listing

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