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Winding up to wind down: designing the end of one's medical career with intentionality.
BMJ Lead
January 2025
University of Louisville Health Sciences Center, Louisville, Kentucky, USA.
Background: Physicians are planful beings, spending much time imagining and trying to design their ideal careers. Yet, despite actuarial expectations that physicians may spend almost two decades in retirement, it is paradoxical that little attention is generally given to designing an ideal retirement.
Methods: The coauthors are physicians in the latter parts of their careers who both teach leadership to physicians and have thought deeply about physician transitions, including retirement.
Latest revisions to the International Health Regulations will fail to prevent future travel chaos.
BMJ Glob Health
January 2025
Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
The poor management of public health risks associated with travel by most countries proved among the most contentious issue areas during the COVID-19 pandemic. Evidence from previous outbreaks suggested travel restrictions were largely unnecessary and counterproductive to timely reporting. This led to initial WHO recommendations against the use of travel restrictions.
View Article and Find Full Text PDFFrontopolar Cortex Interacts With Dorsolateral Prefrontal Cortex to Causally Guide Metacognition.
Hum Brain Mapp
February 2025
Department of Psychology, Ludwig Maximilian University Munich, Munich, Germany.
Accurate metacognitive judgments about an individual's performance in a mental task require the brain to have access to representations of the quality and difficulty of first-order cognitive processes. However, little is known about how accurate metacognitive judgments are implemented in the brain. Here, we combine brain stimulation with functional neuroimaging to determine the neural and psychological mechanisms underlying the frontopolar cortex's (FPC) role in metacognition.
View Article and Find Full Text PDFFrom Structure to Function: Isatin Derivatives as a Promising Class of Antiviral Agents.
Curr Drug Targets
January 2025
School of Pharmaceutical Sciences, Shoolini University, Solan, HP, India.
A range of heterocyclic compounds, including Isatin (oneH-indole-2, 3-dione) and its by-products, have been shown to represent potential unit blocks in the synthesis of potential medicinal agents. Numerous studies have been carried out on isatin, its synthesis, biological uses, and its chemical composition since when it was discovered. Functionally, these isatin-containing heterocycles have demonstrated antibacterial, antidiabetic, antiviral, antitubercular, and anticancer properties, among many others.
View Article and Find Full Text PDFHow Can We Make Information on Equity in Clinical Guidelines More Usable for Clinicians? A Case Study Methodology of General Practitioners.
J Eval Clin Pract
February 2025
School of Primary and Allied Health Care, Monash University, Melbourne, Australia.
Background: Clinical practice guidelines (CPGs) are moving toward greater consideration of population-level differences, like health inequities, when creating management recommendations. CPGs have the potential to reduce or perpetuate health inequities. The intrinsic design factors of electronic interfaces that contain CPGs are known barriers to guideline use.
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